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WIPI2 Antibody (2A2) [CoraFluor™ 1]

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Product Details

Summary
Reactivity Hu, MuSpecies Glossary
Applications ELISA, Flow
Clone
2A2
Clonality
Monoclonal
Host
Mouse
Conjugate
CoraFluor 1

Order Details

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WIPI2 Antibody (2A2) [CoraFluor™ 1] Summary

Description
CoraFluor(TM) 1 is a high performance terbium-based TR-FRET (Time-Resolved Fluorescence Resonance Energy Transfer) or TRF (Time-Resolved Fluorescence) donor for high throughput assay development. CoraFluor(IM) 1 absorbs UV light at approximately 340 nm, and emits at approximately 490 nm, 545 nm, 585 nm and 620 nm. It is compatible with common acceptor dyes that absorb at the emission wavelengths of CoraFluor(TM) 1. CoraFluor(TM) 1 can be used for the development of robust and scalable TR-FRET binding assays such as target engagement, ternary complex, protein-protein interaction and protein quantification assays.
Immunogen
Recombinant fragment (around aa 418-436) of human WIPI2 protein (exact sequence is proprietary) (Uniprot: Q9Y4P8)
Localization
Preautophagosomal structure membrane.
Isotype
IgG1 Kappa
Clonality
Monoclonal
Host
Mouse
Gene
WIPI2
Purity
Protein A or G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • ELISA
  • Flow Cytometry
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark. Do not freeze.
Buffer
PBS
Preservative
No Preservative
Purity
Protein A or G purified

Notes

CoraFluor (TM) is a trademark of Bio-Techne Corp. Sold for research purposes only under agreement from Massachusetts General Hospital. US patent 2022/0025254

Alternate Names for WIPI2 Antibody (2A2) [CoraFluor™ 1]

  • ATG18B
  • Atg21
  • CGI-50
  • DKFZP434J154
  • DKFZp686P02188
  • FLJ12979
  • FLJ14217
  • FLJ42984
  • WD repeat domain phosphoinositide-interacting protein 2
  • WD repeat domain, phosphoinositide interacting 2
  • WD40 repeat protein interacting with phosphoinositides 2
  • WIPI-2
  • WIPI49-like protein 2

Background

WD40 repeat proteins are key components of many essential biologic functions. They regulate the assembly of multiprotein complexes by presenting a beta-propeller platform for simultaneous and reversible protein-protein interactions. Members of the WIPI subfamily of WD40 repeat proteins, such as WIPI2, have a 7-bladed propeller structure and contain a conserved motif for interaction with phospholipids (Proikas-Cezanne et al., 2004 [PubMed 15602573]).[supplied by OMIM]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol WIPI2