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VMAT2 Antibody (CL12531)

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Immunohistochemistry-Paraffin: VMAT2 Antibody (CL12531) [NBP3-18570] - Staining of human cerebral cortex shows no positivity in neurons as expected.
Immunohistochemistry-Paraffin: VMAT2 Antibody (CL12531) [NBP3-18570] - Staining of human cerebral cortex shows no positivity in neurons as expected.
Immunohistochemistry-Paraffin: VMAT2 Antibody (CL12531) [NBP3-18570] - Staining of human dorsal raphe nucleus shows strong cytoplasmic positivity in neurons.
Immunohistochemistry-Paraffin: VMAT2 Antibody (CL12531) [NBP3-18570] - Staining of human stomach tumor (enterochromaffin-like cell carcinoid) shows strong cytoplasmic positivity in tumor cells.
Immunohistochemistry-Paraffin: VMAT2 Antibody (CL12531) [NBP3-18570] - Staining of human cerebellum shows no positivity in Purkinje cells as expected.

Product Details

Summary
Reactivity Hu, RtSpecies Glossary
Applications IHC
Clone
CL12531
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated

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VMAT2 Antibody (CL12531) Summary

Immunogen
This antibody was developed against a sythetic peptide for Q05940. Actual immunogen sequence is proprietary.
Predicted Species
Rat (90%). Backed by our 100% Guarantee.
Isotype
IgG2b
Clonality
Monoclonal
Host
Mouse
Gene
SLC18A2
Purity
Protein A purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
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Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:5000 - 1:10000
  • Immunohistochemistry-Paraffin 1:5000 - 1:10000
Application Notes
For use with IHC-Paraffin, HIER pH 6 retrieval is recommended.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS, pH 7.2, 40% glycerol
Preservative
0.02% Sodium Azide
Purity
Protein A purified

Alternate Names for VMAT2 Antibody (CL12531)

  • MGC120477
  • MNAT
  • monoamine neurotransmitter transporter
  • Monoamine transporter
  • SLC18A2
  • solute carrier family 18 (vesicular monoamine), member 2
  • Solute carrier family 18 member 2
  • SVAT
  • SVMT
  • SVMTMGC120478
  • synaptic vesicular amine transporter
  • VAT2
  • VAT2MGC26538
  • vesicle monoamine transporter type 2
  • vesicle monoamine/H+ antiporter
  • Vesicular amine transporter 2
  • VMAT2

Background

VMAT2 (Vesicular amine transporter 2) acts to accumulate cytosolic monoamines into synaptic vesicles. Its function is essential to the correct activity of the monoaminergic systems that have been implicated in several human neuropsychiatric disorders such as dementia with Lewy bodies. The transporter is a site of action of important drugs, including reserpine and tetrabenazine.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol SLC18A2