Mouse VEGF-C ELISA Kit (Colorimetric)

Vascular endothelial growth factors (VEGFs), also known as vasculotropins, are a family of closely related growth factors having a conserved pattern of eight cysteine residues and sharing common VEGF receptors. VEGFs stimulate the proliferation of endothelial cells, induce angiogenesis, promote cell migration, increase vascular permeability, and inhibit apoptosis. The mitogenic activity of VEGFs appears to be mediated by specific VEGF receptors. The target cell specificity of VEGF is restricted to vascular endothelial cells. Vascular Endothelial Growth Factor C (VEGFC) is a member of the VEGF subfamily of PDGF-related growth factors. It is the ligand for Flt4 (VEGFR3) and KDR (VEGFR2). VEGFC binds Flt4 and induces tyrosine autophosphorylation of VEGFR3 and VEGFR2. VEGFC also stimulates the migration of bovine capillary endothelial cells in collagen gel. It is a specific growth factor for the lymphatic vascular system and mediates lymphangiogenesis. VEGFC is abundantly expressed in heart and skeletal muscle. Other tissues such as lung and kidney also express VEGFC. The human VEGFC gene is located on chromosome 4q34.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. ELISA Kits are guaranteed for 6 months from date of receipt.

We have publications tested in 1 application: ELISA.

Showing Publications 1 - 3 of 3.

Publications using NBP2-78893	Applications	Species
Justin Vercellino, Beata Małachowska, Shilpa Kulkarni, Brett I. Bell, Shahin Shajahan, Kosaku Shinoda, Gary Eichenbaum, Amit K. Verma, Sanchita P. Ghosh, Weng-Lang Yang, Paul S. Frenette, Chandan Guha Thrombopoietin mimetic stimulates bone marrow vascular and stromal niches to mitigate acute radiation syndrome Stem Cell Research & Therapy 2024-04-29 [PMID: 38679747]
Feng W, Jiang D, Xu Y et al. CDK4/6i enhances the antitumor effect of PD1 antibody by promoting TLS formation in ovarian cancer Heliyon 2023-09-01 [PMID: 37809574] (ELISA)	ELISA
yamada H, Naito R, Nishimura M et al. Xenotransplantation of neonatal porcine bone marrow-derived mesenchymal stem cells improves diabetic wound healing by promoting angiogenesis and lymphangiogenesis Xenotransplantation 2022-03-12 [PMID: 35279886]

Images	Ratings	Applications	Species	Date	Details
	5 reviewed by: Verified Customer			07/23/2020	View Summary Sample Tested bEnd.3 mouse endothelioma cell line Lot 168566000

Array NBP2-78893

• VEGF-C Antibodies
• VEGF-C ELISA Kits
• VEGF-C Lysate
• VEGF-C ELISAs
• VEGF-C Proteins and Enzymes