Human VAP-1/AOC3 ELISA Kit (Colorimetric)

Lymphocyte binding to vascular endothelium is a prerequisite for the move- ment of immune cells from the blood into lymphoid tissues and into sites of inflammation. Under inflammatory conditions, cell surface expression of VAP-1 (vascular adhesion protein-1) which is an endothelial sialoglycoprotein, is induced. VAP-1 is a type II transmembrane protein of 84.6 kDa with a single transmembrane domain and N and O-glycosylation sites in the extracellular domain. In vivo, VAP-1 exists predominantly as a 180 kDa homodimer and functions both as an enzyme (monoamine oxidase) and an adhesion molecule for lymphocytes. A circulating form of human Vascular Adhesion Protein-1 (sVAP-1) has been characterized. This sVAP-1 has been shown to be elevated in sera of patients with certain liver diseases and a correlation with the diagnosis of the patients was demonstrated.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. ELISA Kits are guaranteed for 6 months from date of receipt.

Array NBP1-91261

• VAP-1/AOC3 Antibodies
• VAP-1/AOC3 ELISA Kits
• VAP-1/AOC3 Lysate
• VAP-1/AOC3 Protein
• VAP-1/AOC3 ELISAs
• VAP-1/AOC3 Proteins and Enzymes