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USP3 Antibody

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Immunohistochemistry-Paraffin: USP3 Antibody [NB100-77284] - Sample: FFPE section of human ovarian carcinoma. Antibody: Affinity purified rabbit anti- USP3 used at a dilution of 1:1,000 (1ug/ml). Detection: DAB

Product Details

Summary
Reactivity HuSpecies Glossary
Applications IHC, IP, WB (-)
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
1.0 mg/ml
Validated by:
 

Independent Antibodies

       

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USP3 Antibody Summary

Immunogen
The immunogen recognized by this antibody maps to a region between residue 471 and 521 of human ubiquitin specific protease 3 using the numbering given in entry AAD42992.1 (GeneID 9960).
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
USP3
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:1000 - 1:5000
  • Immunohistochemistry-Paraffin 1:1000 - 1:5000
  • Immunoprecipitation 2-5 ug/mg lysate
Application Notes
Epitope retrieval with citrate buffer pH6.0 is recommended for FFPE tissue sections.
Control
USP3 Overexpression Lysate
Publications
Read Publications using
NB100-77284 in the following applications:

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
Tris-Citrate/Phosphate (pH 7.0 - 8.0)
Preservative
0.09% Sodium Azide
Concentration
1.0 mg/ml
Purity
Immunogen affinity purified

Alternate Names for USP3 Antibody

  • Deubiquitinating enzyme 3
  • EC 3.1.2.15
  • EC 3.4.19.12
  • MGC129878
  • MGC129879
  • SIH003
  • ubiquitin carboxyl-terminal hydrolase 3
  • ubiquitin specific peptidase 3
  • ubiquitin specific protease 3
  • ubiquitin thioesterase 3
  • Ubiquitin thiolesterase 3
  • Ubiquitin-specific-processing protease 3
  • UBP
  • USP3

Background

Ubiquitin (Ub) is a highly conserved protein found ubiquitously in eukaryotic organisms. The conjugation of ubiquitin to proteins is an important means to regulate protein activity for many cellular processes by tagging them for degradation. Removal of Ub can rescue proteins from degradation. This is accomplished by the ubiquitin-specific processing protease (UBP) family of enzymes. Ubiquitin specific processing protease 3 (USP3) is a member of this family and is involved in the deubiquitination of histones H2A and H2B.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol USP3
Entrez
Uniprot