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uPAR Antibody Pair [HRP]

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Sandwich ELISA: uPAR Antibody Pair [HRP] [NBP2-79322] - This standard curve is only for demonstration purposes. A standard curve should be generated for each assay.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications ELISA
Conjugate
HRP
Standard Curve Range
4.69-300 pg/ml (example only; lot dependent)
Sensitivity
4.7 pg/ml (example only; lot dependent)

Order Details

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Catalog# & Conjugate Size Price
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uPAR Antibody Pair [HRP] Summary

Description
Solid Phase sandwich ELISA for the quantitative determination of Human uPAR.
Specificity
This solid phase sandwich ELISA utilizes a monoclonal antibody specific for Human uPAR.
Standard Curve Range
4.69-300 pg/ml (example only; lot dependent)
Sensitivity
4.7 pg/ml (example only; lot dependent)
Assay Type
Sandwich ELISA
Sample Volume
100 ul
Gene
PLAUR

Applications/Dilutions

Dilutions
  • ELISA
  • Sandwich ELISA

Packaging, Storage & Formulations

Storage
Storage of components varies. See protocol for specific instructions.

Kit Components

Components
  1. Mouse Monoclonal Capture Antibody
  2. Mouse Monoclonal Detection Antibody (HRP-conjugated)
  3. Standard

Alternate Names for uPAR Antibody Pair [HRP]

  • CD87 antigen
  • CD87
  • Monocyte activation antigen Mo3
  • plasminogen activator, urokinase receptor
  • PLAUR
  • uPAR
  • U-PAR
  • UPARurokinase plasminogen activator surface receptor
  • u-plasminogen activator receptor form 2
  • URKRMO3

Background

uPAR (Urokinase plasminogen activator receptor) is a glycoprotein I anchored surface receptor specific for urokinase plasminogen activator (uPA). Upon binding to uPAR, uPA converts the surface bound, large serum beta globulin plasminogen to plasmin. Plasmin, which is also designated fibrinolysin, is a trypsin-like enzyme that acts on Arg-Lys bonds and induces pericellular proteolysis in fibrin and fibrinogen, and thereby contributes to the systematic activation of the coagulation cascade. uPA and uPAR are known to be overexpressed in mesenchymal and epithelial tumor cells and are required for tumor invasion and metastasis.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Antibody Pairs are guaranteed for 6 months from date of receipt.

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Product General Protocols

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Bioinformatics

Gene Symbol PLAUR