Home » SerpinB2 » SerpinB2 Antibodies » SerpinB2 Antibody (930109) [Unconjugated]

SerpinB2 Antibody (930109) [Unconjugated]

 Submit a Review

Images

 
(
Enlarge)
Western blot shows lysates of U937 human histiocytic lymphoma cell line untreated (-) or treated (+) with PMA and HEK001 human epidermal keratinocyte cell line. PVDF membrane was probed with 2 µg/mL of Mouse Anti-Human Serpin B2 Monoclonal Antibody (Catalog # MAB8550) followed by HRP-conjugated Anti-Mouse IgG Secondary Antibody (Catalog # HAF018). A specific band was detected for Serpin B2 at approximately 45 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1.
Western blot shows lysates of U937 human histiocytic lymphoma cell line untreated (-) or treated (+) with PMA and HEK001 human epidermal keratinocyte cell line. PVDF membrane was probed with 2 µg/mL of Mouse Anti-Human ...read more
U937 human histiocytic lymphoma cell line either untreated (upper panel) or treated with PMA and Calcium Ionomycin for 2 days (lower panel) was stained with Mouse Anti-Human Serpin B2 Monoclonal Antibody (Catalog # ...read more
Serpin B2 was detected in immersion fixed U937 human histiocytic lymphoma cell line stimulated with PMA using Mouse Anti-Human Serpin B2 Monoclonal Antibody (Catalog # MAB8550) at 25 µg/mL for 3 hours at room ...read more
Genetic Strategies: Serpin B2 was detected in immersion fixed K562 human chronic myelogenous leukemia cell line treated with PMA but is not detected in Serpin B2 knockout (KO) K562 cell line using Mouse ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, Flow, CyTOF-ready, ICC/IF, KO
Clone
930109
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Validated by:
     

Genetic Strategies

    

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
FAB8550U-100UG
Alexa Fluor 405
FAB8550V-100UG
Alexa Fluor 488
FAB8550G-100UG
Alexa Fluor 532
FAB8550X
Alexa Fluor 594
FAB8550T-100UG
Alexa Fluor 647
FAB8550R-100UG
Alexa Fluor 700
FAB8550N-100UG
Alexa Fluor 750
FAB8550S-100UG
Allophycocyanin
FAB8550A
Allophycocyanin/Cy7
FAB8550APCCY7
Biotin
FAB8550B
CoraFluor 1
FAB8550CL1
DyLight 350
FAB8550D
DyLight 405
FAB8550E
DyLight 488
FAB8550K
DyLight 550
FAB8550L
DyLight 594
FAB8550M
DyLight 650
FAB8550W
DyLight 680
FAB8550Y
DyLight 755
FAB8550Z
FITC
FAB8550F
HRP
FAB8550H
Janelia Fluor 525
FAB8550JF525
Janelia Fluor 549
FAB8550I
Janelia Fluor 646
FAB8550J
Janelia Fluor 669
FAB8550JF669
PE
FAB8550P
PE/Atto594
FAB8550PEATT594
PE/Cy5.5
FAB8550PECY55
PE/Cy7
FAB8550PECY7
PerCP
FAB8550C
mFluor Violet 450 SE
FAB8550MFV450
mFluor Violet 500 SE
FAB8550MFV500
mFluor Violet 610 SE
FAB8550MFV610
View Available Formulations
Catalog# & Formulation Size Price
Carrier Free
MAB8550-SP
Carrier Free
FAB8550V-100UG
Carrier Free
FAB8550U-100UG
Carrier Free
FAB8550T-100UG
Carrier Free
FAB8550S-100UG
Carrier Free
FAB8550R-100UG
Carrier Free
FAB8550N-100UG
Carrier Free
FAB8550G-100UG
Novus Biologicals offers 100% Guarantee

SerpinB2 Antibody (930109) [Unconjugated] Summary

Immunogen
E. coli-derived recombinant human Serpin B2
Glu2-Ala65, Ala99-Pro415
Accession # P05120
Specificity
Detects human Serpin B2 in direct ELISAs.
Source
N/A
Isotype
IgG2b
Clonality
Monoclonal
Host
Mouse
Gene
SERPINB2
Purity Statement
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
Learn about the Innovator's Reward

Applications/Dilutions

Dilutions
  • CyTOF-ready
  • Flow Cytometry 0.25 ug/10^6 cells
  • Immunocytochemistry 8-25 ug/mL
  • Knockout Validated
  • Western Blot 2 ug/mL

Packaging, Storage & Formulations

Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Preservative
No Preservative
Reconstitution Instructions
Reconstitute at 0.5 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for SerpinB2 Antibody (930109) [Unconjugated]

  • HsT1201
  • Monocyte Arg-serpin
  • PAI
  • PAI2
  • PAI2Urokinase inhibitor
  • Placental plasminogen activator inhibitor
  • PLANH2
  • PLANH2PAI-2
  • plasminogen activator inhibitor 2
  • plasminogen activator inhibitor, type II (arginine-serpin)
  • serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 2
  • Serpin B2
  • serpin peptidase inhibitor, clade B (ovalbumin), member 2
  • Urokinase Inhibitor

Background

Serpin B2, also known as Plasminogen Activator Inhibitor 2 (PAI-2), is a 415 amino acid serine-type endopeptidase inhibitor with high expression in blood, vasculature and placenta. Its expression is upregulated in pregnancy and in activated monocytes/macrophages by a wide range of viral, bacterial and parasitic agents. Serpin B2 is upregulated in monocytes from HIV-1 infected patients, and is thought to modulate Th1/Th2 responses. Serpin B2/PAI-2 colocalizes with CHL1 and Vitronectin and mediates neurite outgrowth during post-natal brain development. Inhibition of uPA by SerpinB2 in tumors is associated with a favorable prognosis.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Customers Who Viewed This Item Also Viewed...

Serpin E1/PAI-1
[HRP]
DSE100
N/A Serpin E1/PAI-1 [HRP]
N/A Serpin E1/PAI-1 [HRP]
(45 Publications)
Species: Hu
Applications: ELISA
u-Plasminogen
Activator/Urokinase [ ...
1310-SE
Enzyme Activity u-Plasminogen Activator/Urokinase [Unconjugated]
(14 Publications)
Species: Hu
Applications: EnzAct
t-Plasminogen
Activator/tPA [HRP]
DTPA00
N/A t-Plasminogen Activator/tPA [HRP]
N/A t-Plasminogen Activator/tPA [HRP]
(7 Publications)
Species: Hu
Applications: ELISA
Angiostatin
Antibody [Unconjugate ...
AF226
Angiostatin Antibody [Unconjugated] - Kringle 1-3
(8 Publications)
Species: Hu
Applications: WB
PRAP1 Antibody
NBP1-80633
Immunohistochemistry-Paraffin PRAP1 Antibody
(2 Publications)
Species: Hu
Applications: IHC, IHC-P
Recombinant Human
PRH2 GST (N-Term) Pro ...
H00005555-P01
SDS-PAGE Recombinant Human PRH2 GST (N-Term) Protein
Species: Hu
Applications: ELISA, AP, PA, PAGE, WB
uPAR [HRP]
DUP00
N/A uPAR [HRP]
N/A uPAR [HRP]
(44 Publications)
Species: Hu
Applications: ELISA
Pallidin Antibody
(OTI1H9)
NBP2-01763
Western Blot Pallidin Antibody (OTI1H9)
Flow Cytometry Pallidin Antibody (OTI1H9)
Immunohistochemistry-Paraffin Pallidin Antibody (OTI1H9)
Species: Hu, Mu, Rt
Applications: Flow, IHC, IHC-P, WB
Pancreatic Amylase
Alpha Antibody (OTI6D ...
NBP1-47659
Immunohistochemistry-Paraffin Pancreatic Amylase Alpha Antibody (OTI6D4)
Immunohistochemistry-Paraffin Pancreatic Amylase Alpha Antibody (OTI6D4)
Immunohistochemistry-Paraffin Pancreatic Amylase Alpha Antibody (OTI6D4)
(1 Review)
Species: Hu
Applications: IHC, IHC-P, WB
Recombinant Human
PRH1 His Protein
NBP2-23368
SDS-PAGE Recombinant Human PRH1 His Protein
Species: Hu
Applications: PAGE
EPB42 Antibody
(2G12)
H00002038-M01
Western Blot EPB42 Antibody (2G12)
ELISA EPB42 Antibody (2G12)
Immunocytochemistry/ Immunofluorescence EPB42 Antibody (2G12)
Species: Hu
Applications: ELISA, ICC/IF, WB
TNF-alpha
[Unconjugated]
210-TA
SDS-PAGE TNF-alpha [Unconjugated]
Bioactivity TNF-alpha [Unconjugated]
SEC-MALS TNF-alpha [Unconjugated]
(3 Reviews)
(821 Publications)
Species: Hu
Applications: BA
Serpin
C1/Antithrombin-III A ...
AF1267
Serpin C1/Antithrombin-III Antibody [Unconjugated]
(7 Publications)
Species: Hu
Applications: IP, Neut, WB
Coagulation Factor
II/Thrombin Antibody ...
AF1148
Simple Western Coagulation Factor II/Thrombin Antibody [Unconjugated]
Flow Cytometry Coagulation Factor II/Thrombin Antibody [Unconjugated]
Western Blot Coagulation Factor II/Thrombin Antibody [Unconjugated]
(1 Publication)
Species: Hu
Applications: CyTOF-ready, Flow, Simple Western, WB
Von Willebrand
Factor Antibody
NB600-586
Dual RNAscope ISH-IHC Von Willebrand Factor Antibody
Immunohistochemistry-Frozen Von Willebrand Factor Antibody
Immunohistochemistry Von Willebrand Factor Antibody
(3 Reviews)
(14 Publications)
Species: Ca, Fe, Hu, Mu
Applications: Dual ISH-IHC, ICC/IF, IHC, IHC-Fr, IHC-P
Insulin Antibody
(182410) [Unconjugate ...
MAB1417
Immunocytochemistry Insulin Antibody (182410) [Unconjugated]
Immunohistochemistry Insulin Antibody (182410) [Unconjugated]
(25 Publications)
Species: Bv, Hu, Mu
Applications: CyTOF-ready, ICC, IHC, ICFlow
Coagulation Factor
III/Tissue Factor [HR ...
DCF300
N/A Coagulation Factor III/Tissue Factor [HRP]
N/A Coagulation Factor III/Tissue Factor [HRP]
(27 Publications)
Species: Hu
Applications: ELISA
IL-6 [HRP]
M6000B
N/A IL-6 [HRP]
N/A IL-6 [HRP]
N/A IL-6 [HRP]
(676 Publications)
Species: Mu
Applications: ELISA
ATAT1 Antibody
NBP2-48990
Immunocytochemistry/ Immunofluorescence ATAT1 Antibody
Immunohistochemistry-Paraffin ATAT1 Antibody
Immunohistochemistry-Paraffin ATAT1 Antibody
Species: Hu
Applications: ICC/IF, IHC, IHC-P
SerpinB2 Antibody
(930109) [Unconjugate ...
MAB8550
SerpinB2 Antibody (930109) [Unconjugated]
Species: Hu
Applications: WB, Flow, CyTOF-ready, ICC/IF, KO

Publications for SerpinB2 Antibody (MAB8550) (0)

There are no publications for SerpinB2 Antibody (MAB8550).
By submitting your publication information earn gift cards and discounts for future purchases.

Reviews for SerpinB2 Antibody (MAB8550) (0)

There are no reviews for SerpinB2 Antibody (MAB8550). By submitting a review you will receive an Amazon e-Gift Card or Novus Product Discount.
  • Review with no image -- $10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen
  • Review with an image -- $25/€18/£15/$25 CAD/¥150 Yuan/¥2500 Yen

Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

WB Video Protocol

FAQs for SerpinB2 Antibody (MAB8550) (0)

There are no specific FAQs related to this product. Read our general customer & technical service FAQs.

Secondary Antibodies

 

Isotype Controls

Additional SerpinB2 Products

Blogs on SerpinB2

There are no specific blogs for SerpinB2, but you can read our latest blog posts.
Read our latest blog and use the new citation tool on bio-techne.com

Customers Who Bought This Also Bought

Contact Information

Product PDFs

  PDF SDS
  PDF Datasheet
  Request CofA

Calculators

Concentration Calculator

The concentration calculator allows you to quickly calculate the volume, mass or concentration of your vial. Simply enter your mass, volume, or concentration values for your reagent and the calculator will determine the rest.

=
÷

Review this Product

Be the first to review our SerpinB2 Antibody (930109) [Unconjugated] and receive a gift card or discount.


Bioinformatics

Gene Symbol SERPINB2
Uniprot