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Human t-Plasminogen Activator/tPA Quantikine ELISA Kit

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Summary
Reactivity HuSpecies Glossary
Applications ELISA
Conjugate
HRP

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Human t-Plasminogen Activator/tPA Quantikine ELISA Kit Summary

Background
The Quantikine Human t-Plasminogen Activator/tPA Immunoassay is a 4.5 hour solid phase ELISA designed to measure tPA levels in cell culture supernates, serum, plasma, saliva, urine, and human milk. It contains CHO cell-expressed recombinant human tPA and antibodies raised against the recombinant protein. Results obtained for naturally occurring human tPA showed linear curves that were parall...el to the standard curves obtained using the Quantikine Human tPA Immunoassay standards. These results indicate that this kit can be used to determine relative mass values for natural human tPA.
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Specificity
Natural and recombinant human tPA. This assay also recognizes tPA complexed with PAI-1.
Source
N/A
Assay Type
Solid Phase Sandwich ELISA
Inter-Assay
See PDF Datasheet for details
Intra-Assay
See PDF Datasheet for details
Spike Recovery
See PDF Datasheet for details
Sample Volume
See PDF Datasheet for details
Gene
PLAT

Applications/Dilutions

Dilutions
  • ELISA
Application Notes
No significant interference observed with available related molecules.
Publications
Read Publications using DTPA00.

Packaging, Storage & Formulations

Storage
Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Human t-Plasminogen Activator/tPA Quantikine ELISA Kit

  • Alteplase
  • DKFZp686I03148
  • EC 3.4.21
  • EC 3.4.21.68
  • plasminogen activator, tissue type
  • plasminogen activator, tissue
  • PLAT
  • Reteplase
  • tissue plasminogen activator (t-PA)
  • tissue-type plasminogen activator
  • TPA
  • T-PA
  • tPlasminogen Activator
  • t-Plasminogen Activator

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⚠ WARNING: This product can expose you to chemicals including N,N-Dimethylforamide, which is known to the State of California to cause cancer. For more information, go to www.P65Warnings.ca.gov.

Publications for t-Plasminogen Activator/tPA (DTPA00)(7)

We have publications tested in 1 confirmed species: Human.


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Human
(7)
All Species
Showing Publications 1 - 7 of 7.
Publications using DTPA00 Applications Species
Li, H;Zhao, M;Jiang, C;Zhao, H;Wu, C;Li, Y;Zhang, S;Xu, P;Mou, T;Xu, Y;Huang, M; Elevated Plasma Levels of Mature Brain-Derived Neurotrophic Factor in Major Depressive Disorder Patients with Higher Suicidal Ideation Brain sciences 2023-08-21 [PMID: 37626579] (Human) Human
V Montiel, I Lobysheva, L Gérard, M Vermeersch, D Perez-Morg, T Castelein, JB Mesland, P Hantson, C Collienne, D Gruson, MA van Dievoe, A Persu, C Beauloye, M Dechamps, L Belkhir, A Robert, M Derive, PF Laterre, AHJ Danser, X Wittebole, JL Balligand Oxidative stress-induced endothelial dysfunction and decreased vascular nitric oxide in COVID-19 patients EBioMedicine, 2022-02-23;77(0):103893. 2022-02-23 [PMID: 35219085] (Human) Human
EE Tzekaki, M Tsolaki, &alphaA Pantazaki, G Geromichal, E Lazarou, M Kozori, Z Sinakos The pleiotropic beneficial intervention of olive oil intake on the Alzheimer's disease onset via fibrinolytic system Experimental gerontology, 2021-04-06;150(0):111344. 2021-04-06 [PMID: 33836262] (Human) Human
C Voukalis, GYH Lip, E Shantsila Effects of antithrombotic drugs on the prothrombotic state in patients with atrial fibrillation: The west Birmingham atrial fibrillation project Thrombosis Research, 2021-02-09;200(0):149-155. 2021-02-09 [PMID: 33610887] (Human) Human
C Wu, J Lu, S Lu, M Huang, Y Xu Increased ratio of mature BDNF to precursor-BDNF in patients with major depressive disorder with severe anhedonia J Psychiatr Res, 2020-05-12;126(0):92-97. 2020-05-12 [PMID: 32428748] (Human) Human
S Chen, H Jiang, Y Liu, Z Hou, Y Yue, Y Zhang, F Zhao, Z Xu, Y Li, X Mou, L Li, T Wang, J Zhao, C Han, Y Sui, M Wang, Z Yang, Y Lu, Y Zhu, J Li, X Shen, F Sun, Q Chen, H Chen, Y Yuan Combined serum levels of multiple proteins in tPA-BDNF pathway may aid the diagnosis of five mental disorders Sci Rep, 2017-07-31;7(1):6871. 2017-07-31 [PMID: 28761093] (Human) Human
H Jiang, S Chen, C Li, N Lu, Y Yue, Y Yin, Y Zhang, X Zhi, D Zhang, Y Yuan The serum protein levels of the tPA-BDNF pathway are implicated in depression and antidepressant treatment Transl Psychiatry, 2017-04-04;7(4):e1079. 2017-04-04 [PMID: 28375203] (Human) Human

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Bioinformatics

Gene Symbol PLAT