TRIM Antibody

Images

 
Immunohistochemistry-Paraffin: TRIM Antibody [NBP3-17096] - Staining of human lymph node shows high expression.
Immunohistochemistry-Paraffin: TRIM Antibody [NBP3-17096] - Analysis in human lymph node and cerebral cortex tissues using Anti-TRAT1 antibody. Corresponding TRAT1 RNA-seq data are presented for the same tissues.
Immunohistochemistry-Paraffin: TRIM Antibody [NBP3-17096] - Staining of human cerebral cortex shows low expression as expected.
Immunohistochemistry-Paraffin: TRIM Antibody [NBP3-17096] - Staining of human thymus shows membranous positivity in medulla and cortex.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

TRIM Antibody Summary

Immunogen
This antibody was developed against Recombinant Protein corresponding to amino acids: IDASVSKTTLVDSFSPESQAVEENIHDDPIRLFGLIRAKREPIN
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
TRAT1
Purity
Affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:1000 - 1:2500
  • Immunohistochemistry-Paraffin 1:1000 - 1:2500
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS, pH 7.2, 40% glycerol
Preservative
0.02% Sodium Azide
Purity
Affinity purified

Alternate Names for TRIM Antibody

  • pp29/30
  • T cell receptor associated transmembrane adaptor 1
  • T cell receptor interacting molecule
  • T-cell receptor interacting molecule
  • T-cell receptor-associated transmembrane adapter 1
  • T-cell receptor-interacting molecule
  • TCRIM
  • TRAT1
  • TRIM
  • TRIMHSPC062

Background

TRIM is a 30 kD disulfide-linked protein also known as T cell receptor interacting molecule. TRIM is a type III membrane protein containing a very short extracellular domain (8 amino acids). TRIM is highly expressed in T cells with some expression also observed in NK cells. TRIM is a signaling adaptor molecule that links extracellular and intracellular signaling. The TRIM protein is phosphorylated by Src kinases and associates with the PI3K regulatory subunit alpha after phosphorylation. TRIM has also been shown to associate with TCR alpha, beta, and zeta. The TRIM-4 monoclonal antibody recognizes human TRIM and has been shown to be useful for Western blotting, intracellular staining by flow cytometry, and immunofluorescence staining.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol TRAT1