TRIM21/SSA1 Antibody

This gene encodes a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The encoded protein is part of the RoSSA ribonucleoprotein, which includes a single polypeptide and one of four small RNA molecules. The RoSSA particle localizes to both the cytoplasm and the nucleus. RoSSA interacts with autoantigens in patients with Sjogren syndrome and systemic lupus erythematosus. Alternatively spliced transcript variants for this gene have been described but the full-length nature of only one has been determined.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 2 confirmed species: Human, Mouse.

We have publications tested in 5 applications: Co-IP, IHC, IP, KD, WB.

Showing Publications 1 - 4 of 4.

Publications using NBP1-33548	Applications	Species
Ho S, Chaput D, Sinkey R et al. Proteomic studies of human placentas reveal partnerships associated with preeclampsia, diabetes, gravidity, and labor medRxiv 2023-07-27 (IHC, Human)	IHC	Human
Ho SJ, Chaput D, Sinkey RG et al. Proteomic studies of VEGFR2 in human placentas reveal protein associations with preeclampsia, diabetes, gravidity, and labor. Cell communication and signaling : CCS 2024-04-11 [PMID: 38594674]
Liu RX, Gu RH, Li ZP et al. Trim21 depletion alleviates bone loss in osteoporosis via activation of YAP1/?-catenin signaling Bone research 2023-10-26 [PMID: 37884520] (Co-IP, WB, Mouse)	Co-IP, WB	Mouse
Li JT, Yin M, Wang D et al. BCAT2-mediated BCAA catabolism is critical for development of pancreatic ductal adenocarcinoma Nat. Cell Biol. 2020-02-01 [PMID: 32029896] (KD, IP, Mouse, Human)	KD, IP	Mouse, Human

Array NBP1-33548

• TRIM21/SSA1 Antibodies
• TRIM21/SSA1 ELISA Kit
• TRIM21/SSA1 Lysate
• TRIM21/SSA1 Proteins