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Transglutaminase 7/TGM7 Antibody (602708)

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Western blot shows lysates of PC-3 human prostate cancer cell line. PVDF Membrane was probed with 2 µg/mL of Rat Anti-Human Transglutaminase 7/TGM7 Monoclonal Antibody (Catalog # MAB5426) followed by HRP-conjugated ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB
Clone
602708
Clonality
Monoclonal
Host
Rat
Conjugate
Unconjugated
Concentration
LYOPH

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Catalog# & Formulation Size Price
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Transglutaminase 7/TGM7 Antibody (602708) Summary

Immunogen
S. frugiperda insect ovarian cell line Sf 21-derived recombinant human Transglutaminase 7/TGM7
Asp2-Pro710
Accession # Q96PF1
Specificity
Detects human Transglutaminase 7/TGM7 in direct ELISAs and Western blots. In direct ELISAs, no cross‑reactivity with recombinant human TGM2, 3, 4, or recombinant mouse TGM2 is observed.
Source
N/A
Isotype
IgG2a
Clonality
Monoclonal
Host
Rat
Gene
TGM7
Purity Statement
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 2 ug/mL

Packaging, Storage & Formulations

Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Preservative
No Preservative
Concentration
LYOPH
Reconstitution Instructions
Reconstitute at 0.5 mg/mL in sterile PBS

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Transglutaminase 7/TGM7 Antibody (602708)

  • protein-glutamine gamma-glutamyltransferase Z
  • TG(Z)
  • TGase Z
  • TGase-7
  • TGM7
  • TGMZ
  • TGMZEC 2.3.2.13
  • TGZ
  • Transglutaminase 7
  • Transglutaminase Z
  • transglutaminase-7

Background

Transglutaminase 7 (TGM7), also known as protein-glutamine gamma -glutamyltransferase Z, TGase Z and TGZ, is an 80 kDa, widely expressed member of the Transglutaminase superfamily and family. Human Transglutaminase 7 is 710 amino acids (aa) in length and contains a Transglutaminase family, C-terminal Ig like domain (aa 608‑705). Human Transglutaminase 7 shares 78% aa identity with mouse Transglutaminase 7. Like other Transglutaminases, Transglutaminase 7 is an enzyme that stabilizes protein assembly through the formation of intra- or intermolecular N epsilon ( gamma -glutamyl)lysine bonds. It catalyzes a calcium-dependent transferase reaction between the gamma -carboxamide group of a peptide-bound glutamine residue and various primary amines, most commonly the epsilon -amino group of lysine residues.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol TGM7
Uniprot