Home » TRAILR4/TNFRSF10D/DcR2 » TRAILR4/TNFRSF10D/DcR2 Antibodies » TRAILR4/TNFRSF10D/DcR2 Antibody (104918) [Allophycocyanin]
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TRAILR4/TNFRSF10D/DcR2 Antibody (104918) [Allophycocyanin]

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Human peripheral blood granulocytes were stained with Mouse Anti-Human TRAIL R4/TNFRSF10D APC‑conjugated Monoclonal Antibody (Catalog # FAB633A, filled histogram) or isotype control antibody (Catalog # IC002A, open histogram). View our protocol for Staining Membrane-associated Proteins.
Human peripheral blood granulocytes were stained with Mouse Anti-Human TRAIL R4/TNFRSF10D APC‑conjugated Monoclonal Antibody (Catalog # FAB633A, filled histogram) or isotype control antibody (Catalog # IC002A, ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow
Clone
104918
Clonality
Monoclonal
Host
Mouse
Conjugate
Allophycocyanin

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
FAB633U-100UG
Alexa Fluor 405
FAB633V-100UG
Alexa Fluor 488
FAB633G-100UG
Alexa Fluor 532
FAB633X
Alexa Fluor 594
FAB633T-100UG
Alexa Fluor 647
FAB633R-100UG
Alexa Fluor 700
FAB633N-100UG
Alexa Fluor 750
FAB633S-100UG
Allophycocyanin/Cy7
FAB633APCCY7
Biotin
FAB633B
DyLight 350
FAB633D
DyLight 405
FAB633E
DyLight 488
FAB633K
DyLight 550
FAB633L
DyLight 594
FAB633M
DyLight 650
FAB633W
DyLight 680
FAB633Y
DyLight 755
FAB633Z
FITC
FAB633F
HRP
FAB633H
Janelia Fluor 525
FAB633JF525
Janelia Fluor 549
FAB633I
Janelia Fluor 646
FAB633J
Janelia Fluor 669
FAB633JF669
PE/Atto594
FAB633PEATT594
PE/Cy5.5
FAB633PECY55
PE/Cy7
FAB633PECY7
Phycoerythrin
FAB633P
Unconjugated
MAB633
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
MAB633
Carrier Free
FAB633G-100UG
Carrier Free
FAB633P
Carrier Free
MAB633
Carrier Free
MAB633-SP
Carrier Free
FAB633V-100UG
Carrier Free
FAB633U-100UG
Carrier Free
FAB633T-100UG
Carrier Free
FAB633S-100UG
Carrier Free
FAB633R-100UG
Carrier Free
FAB633N-100UG
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TRAILR4/TNFRSF10D/DcR2 Antibody (104918) [Allophycocyanin] Summary

Immunogen
Mouse myeloma cell line NS0-derived recombinant human TRAIL R4/TNFRSF10D
Ala56-His211
Accession # Q9UBN6
Specificity
Detects human TRAIL R4/TNFRSF10D in ELISAs and Western blots. In sandwich immunoassays, less than 5% cross-reactivity with recombinant human (rh) TRAIL R1, rhTRAIL R2, TRAIL R3, rhTRAIL, rhTNF‑ alpha , and rhTNF-beta is observed.
Source
N/A
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
TNFRSF10D
Purity Statement
Protein A or G purified from ascites
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
Learn about the Innovator's Reward

Applications/Dilutions

Dilutions
  • Flow Cytometry 10 uL/10^6 cells
Publications
Read Publications using
FAB633A in the following applications:

Packaging, Storage & Formulations

Storage
Protect from light. Do not freeze.
  • 12 months from date of receipt, 2 to 8 °C as supplied.
Buffer
Supplied in a saline solution containing BSA and Sodium Azide.
Preservative
Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for TRAILR4/TNFRSF10D/DcR2 Antibody (104918) [Allophycocyanin]

  • CD264 antigen
  • CD264
  • DcR2
  • DCR2decoy with truncated death domain
  • Decoy receptor 2
  • TNF receptor-related receptor for TRAIL
  • TNF-related apoptosis-inducing ligand receptor 4
  • TNFRSF10D
  • TRAIL R4
  • TRAILR4
  • TRAIL-R4
  • TRAILR4TRAIL receptor 4
  • TRUNDDTRAIL receptor with a truncated death domain
  • tumor necrosis factor receptor superfamily member 10D
  • tumor necrosis factor receptor superfamily, member 10d, decoy with truncateddeath domain

Background

Human TRAIL R4, also called Decoy Receptor 2 (DcR2) and TRUNND (TRAIL Receptor with a Truncated Death Domain), is a type I, TNF R family transmembrane protein, which is a receptor for TRAIL (APO2 Ligand). In the TNF superfamily nomenclature, TRAIL R4 is designated as TNFRSF10D. TRAIL R4 is unique among the TRAIL receptors in that its cytoplasmic domain contains a truncated consensus death domain motif. Binding of TRAIL R4 does not result in an apoptotic signal. Overexpression of TRAIL R4 can protect cells bearing TRAIL R1 and/or TRAIL R2 from TRAIL-mediated apoptosis. The human soluble TRAIL R4/Fc chimera neutralizes the ability of TRAIL to induce apoptosis.

  1. Griffith, T.S. et al. (1998) Curr. Opin. Immunol. 10:559.
  2. Pan, G. et al. (1998) FEBS lett 424:41.
  3. Marsters, S.A. et al. (1997) Cur. Biol. 7:1003.
  4. Degli-Esposti, M.A. et al. (1997) Immunity 7:813.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for TRAILR4/TNFRSF10D/DcR2 Antibody (FAB633A)(3)

We have publications tested in 1 confirmed species: Human.

We have publications tested in 1 application: Flow Cytometry.


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Secondary Antibodies

 

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Bioinformatics

Gene Symbol TNFRSF10D
Uniprot