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TR2/NR2C1 Antibody (H0037) [Unconjugated]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, IP, ELISA
Clone
H0037
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Suitable Sample Type
23005

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TR2/NR2C1 Antibody (H0037) [Unconjugated] Summary

Immunogen
Recombinant human TR2/NR2C1
aa 4-110
Specificity
This antibody specifically recognizes human TR2. Not yet tested in other species.
Source
N/A
Isotype
IgG2b
Clonality
Monoclonal
Host
Mouse
Gene
NR2C1
Purity Statement
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot
  • Immunoprecipitation
  • Direct ELISA

Packaging, Storage & Formulations

Storage
This antibody is stable for greater than six months when held at -20 °C in a manual defrost freezer or at -70 °C. Upon thawing, the antibody can be stored at 2-8 °C for at least 1 month without detectable loss of activity. Avoid repeated freeze-thaw cycles.
Buffer
A liquid formulation in physiologic saline with 0.1% NaN3.
Preservative
0.1% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for TR2/NR2C1 Antibody (H0037) [Unconjugated]

  • NR2C1
  • nuclear receptor subfamily 2 group C member 1
  • nuclear receptor subfamily 2, group C isoform
  • nuclear receptor subfamily 2, group C, member 1
  • Orphan nuclear receptor TR2
  • Testicular receptor 2
  • TR2 nuclear hormone receptor
  • TR2
  • TR2-11

Background

Human Testicular Receptor 2 (TR2, TR2-11; NR2C1) is a 67 - 70 kDa, 603 amino acid member of the NR2 subfamily of the Nuclear Hormone Receptor superfamily. It is expressed in prostate and testis, forms homodimers with itself, and heterodimers with TR4. In addition to TR2-11, there are three other isoforms. All exhibit a DNA binding domain (DBD) (amino acids 111 - 179) and a variable length ligand binding domain (LBD) (amino acids 261 – 603). TR2-7 is truncated at 184 amino acids in length, with amino acids 1 - 181 showing complete identity to TR2-11. There is no LBD. TR2-9 is 467 amino acids in length and is identical to TR2-11 over amino acids 1 – 464. TR2-5 is 483 amino acids in length and identical to TR2-11 over amino acids 1 - 466. Their significance is unclear.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol NR2C1