TR2/NR2C1 Antibody (H0037) [Unconjugated] Summary
Immunogen |
Recombinant human TR2/NR2C1 aa 4-110 |
Specificity |
This antibody specifically recognizes human TR2. Not yet tested in other
species. |
Source |
N/A |
Isotype |
IgG2b |
Clonality |
Monoclonal |
Host |
Mouse |
Gene |
NR2C1 |
Purity Statement |
Protein A or G purified from hybridoma culture supernatant |
Innovator's Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase. |
Applications/Dilutions
Dilutions |
- Western Blot
- Immunoprecipitation
- Direct ELISA
|
Packaging, Storage & Formulations
Storage |
This antibody is stable for greater than six months when held at -20 °C in a
manual defrost freezer or at -70 °C. Upon thawing, the antibody can be
stored at 2-8 °C for at least 1 month without detectable loss of activity. Avoid
repeated freeze-thaw cycles. |
Buffer |
A liquid formulation in physiologic saline with 0.1% NaN3. |
Preservative |
0.1% Sodium Azide |
Notes
This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.
Alternate Names for TR2/NR2C1 Antibody (H0037) [Unconjugated]
Background
Human Testicular Receptor 2 (TR2, TR2-11; NR2C1) is a 67 - 70 kDa,
603 amino acid member of the NR2 subfamily of the Nuclear Hormone
Receptor superfamily. It is expressed in prostate and testis, forms homodimers
with itself, and heterodimers with TR4. In addition to TR2-11, there are three
other isoforms. All exhibit a DNA binding domain (DBD) (amino acids
111 - 179) and a variable length ligand binding domain (LBD) (amino acids
261 – 603). TR2-7 is truncated at 184 amino acids in length, with amino acids
1 - 181 showing complete identity to TR2-11. There is no LBD. TR2-9 is
467 amino acids in length and is identical to TR2-11 over amino acids 1 – 464.
TR2-5 is 483 amino acids in length and identical to TR2-11 over amino acids
1 - 466. Their significance is unclear.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are
guaranteed for 1 year from date of receipt.
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Secondary Antibodies
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Isotype Controls
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