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TPPP/p25 Antibody

Images

 
Western Blot: TPPP/p25 Antibody [NBP1-80962] - Lane 1: Marker [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11. Lane 2: Human cell line RT-592
Immunohistochemistry-Paraffin: TPPP/p25 Antibody [NBP1-80962] - Staining of human liver shows no positivity in hepatocytes as expected.
Immunohistochemistry-Paraffin: TPPP/p25 Antibody [NBP1-80962] - Staining of human cerebral cortex shows nuclear and cytoplasmic positivity in neurons.
Immunohistochemistry-Paraffin: TPPP/p25 Antibody [NBP1-80962] - Staining of human lymph node.
Immunohistochemistry-Paraffin: TPPP/p25 Antibody [NBP1-80962] - Staining of human placenta shows no positivity in trophoblastic cells and weak cytoplasmic and nuclear staining in Hofbauer cells.
Immunohistochemistry-Paraffin: TPPP/p25 Antibody [NBP1-80962] - Staining of human pancreas shows cytoplasmicand nuclear positivity in islets of Langerhans.
Immunohistochemistry-Paraffin: TPPP/p25 Antibody [NBP1-80962] - Staining of human fallopian tube shows cytoplasmic positivity in glandular cells.
Immunohistochemistry-Paraffin: TPPP/p25 Antibody [NBP1-80962] - Staining of human liver.
Immunohistochemistry-Paraffin: TPPP/p25 Antibody [NBP1-80962] - Staining of human colon.
Independent Antibodies: Immunohistochemistry-Paraffin: TPPP/p25 Antibody [NBP1-80962] - Staining of human cerebral cortex, liver, lower gastrointestinal and pancreas using Anti-TPPP antibody NBP1-80962 (A) shows ...read more
Orthogonal Strategies: Immunohistochemistry-Paraffin: TPPP/p25 Antibody [NBP1-80962] - Analysis in human cerebral cortex and liver tissues using NBP1-80962 antibody. Corresponding TPPP RNA-seq data are presented ...read more
Immunohistochemistry-Paraffin: TPPP/p25 Antibody [NBP1-80962] - Staining of human cerebral cortex shows strong cytoplasmic and nuclear positivity in glial cells.
Immunohistochemistry-Paraffin: TPPP/p25 Antibody [NBP1-80962] - Staining of human lower gastrointestinal shows moderate cytoplasmic positivity in peripheral ganglion.

Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

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TPPP/p25 Antibody Summary

Immunogen
This antibody was developed against Recombinant Protein corresponding to amino acids: SLESEGAGEGAAASPELSALEEAFRRFAVHGDARATGREMHGKNWSKLC
Predicted Species
Mouse (90%), Rat (92%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
TPPP
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:5000 - 1:10000
  • Immunohistochemistry-Paraffin 1:5000 - 1:10000
  • Western Blot 0.04-0.4 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Theoretical MW
26 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Control Peptide
TPPP/p25 Protein (NBP1-80962PEP)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for TPPP/p25 Antibody

  • p24
  • P24,25 kDa brain-specific protein
  • p25
  • p25alpha
  • p25-alpha
  • TPPP/p25brain specific protein p25 alpha
  • TPPP1glycogen synthase kinase 3 (GSK3) inhibitor p24
  • tubulin polymerization promoting protein
  • tubulin polymerization-promoting protein

Background

TPPP may play a role in the polymerization of tubulin into microtubules, microtubule bundling and the stabilization of existing microtubules, thus maintaining the integrity ofthe microtubule network. May play a role in mitotic spindle assembly and nuclear env

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol TPPP
Entrez
Uniprot