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TGF-beta 1 Antibody (OTI1E12) [Janelia Fluor® 549]

Name: TGF-beta 1 Antibody (OTI1E12) [Janelia Fluor&#174; 549]
Brand: Novus Biologicals
SKU: NBP2-74495JF549
Price: 679 USD

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Product Details

Summary

Reactivity	Hu, Mu, RtSpecies Glossary
Applications	WB, Flow, ICC/IF
Clone	OTI1E12
Clonality	Monoclonal
Host	Mouse
Conjugate	Janelia Fluor 549

Order Details

View Available Conjugates

Catalog# & Conjugate	Size	Price
Alexa Fluor 350 NBP2-74495AF350

Alexa Fluor 405 NBP2-74495AF405

Alexa Fluor 488 NBP2-74495AF488

Alexa Fluor 532 NBP2-74495AF532

Alexa Fluor 594 NBP2-74495AF594

Alexa Fluor 647 NBP2-74495AF647

Alexa Fluor 700 NBP2-74495AF700

Alexa Fluor 750 NBP2-74495AF750

Allophycocyanin NBP2-74495APC

Allophycocyanin/Cy7 NBP2-74495APCCY7

Biotin NBP2-74495B

CoraFluor 1 NBP2-74495CL1

DyLight 350 NBP2-74495UV

DyLight 405 NBP2-74495V

DyLight 488 NBP2-74495G

DyLight 550 NBP2-74495R

DyLight 594 NBP2-74495DL594

DyLight 650 NBP2-74495C

DyLight 680 NBP2-74495FR

DyLight 755 NBP2-74495IR

FITC NBP2-74495F

HRP NBP2-74495H

Janelia Fluor 525 NBP2-74495JF525

Janelia Fluor 646 NBP2-74495JF646

Janelia Fluor 669 NBP2-74495JF669

PE NBP2-74495PE

PE/Atto594 NBP2-74495PEATT594

PE/Cy5.5 NBP2-74495PECY55

PE/Cy7 NBP2-74495PECY7

PerCP NBP2-74495PCP

Unconjugated NBP2-46108

mFluor Violet 450 SE NBP2-74495MFV450

mFluor Violet 500 SE NBP2-74495MFV500

mFluor Violet 610 SE NBP2-74495MFV610

View Available Formulations

Catalog# & Formulation	Size	Price
Standard Formulation NBP2-46108

Azide and BSA Free NBP2-74495

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Conjugate	Catalog #	Availability	Size	Price
Alexa Fluor 350	NBP2-74495AF350
Alexa Fluor 405	NBP2-74495AF405
Alexa Fluor 488	NBP2-74495AF488
Alexa Fluor 532	NBP2-74495AF532
Alexa Fluor 594	NBP2-74495AF594
Alexa Fluor 647	NBP2-74495AF647
Alexa Fluor 700	NBP2-74495AF700
Alexa Fluor 750	NBP2-74495AF750
Allophycocyanin	NBP2-74495APC
Allophycocyanin/Cy7	NBP2-74495APCCY7
Biotin	NBP2-74495B
CoraFluor 1	NBP2-74495CL1
DyLight 350	NBP2-74495UV
DyLight 405	NBP2-74495V
DyLight 488	NBP2-74495G
DyLight 550	NBP2-74495R
DyLight 594	NBP2-74495DL594
DyLight 650	NBP2-74495C
DyLight 680	NBP2-74495FR
DyLight 755	NBP2-74495IR
FITC	NBP2-74495F
HRP	NBP2-74495H
Janelia Fluor 525	NBP2-74495JF525
Janelia Fluor 646	NBP2-74495JF646
Janelia Fluor 669	NBP2-74495JF669
PE	NBP2-74495PE
PE/Atto594	NBP2-74495PEATT594
PE/Cy5.5	NBP2-74495PECY55
PE/Cy7	NBP2-74495PECY7
PerCP	NBP2-74495PCP
Unconjugated	NBP2-46108
mFluor Violet 450 SE	NBP2-74495MFV450
mFluor Violet 500 SE	NBP2-74495MFV500
mFluor Violet 610 SE	NBP2-74495MFV610

TGF-beta 1 Antibody (OTI1E12) [Janelia Fluor® 549] Summary

Immunogen	Full length recombinant protein of human TGF-beta 1 (NP_000651) produced in HEK293T cells.
Isotype	IgG2a
Clonality	Monoclonal
Host	Mouse
Gene	TGFB1
Purity	Immunogen affinity purified
Innovator's Reward	Test in a species/application not listed above to receive a full credit towards a future purchase. Learn about the Innovator's Reward

Applications/Dilutions

Dilutions	Flow Cytometry Immunocytochemistry/ Immunofluorescence Western Blot
Application Notes	Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

Please note that this antibody is reactive to Mouse and derived from the same host, Mouse. Mouse-On-Mouse blocking reagent may be needed for IHC and ICC experiments to reduce high background signal. You can find these reagents under catalog numbers PK-2200-NB and MP-2400-NB. Please contact Technical Support if you have any questions.

Packaging, Storage & Formulations

Storage	Store at 4C in the dark.
Buffer	50mM Sodium Borate
Preservative	0.05% Sodium Azide
Purity	Immunogen affinity purified

Notes

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for TGF-beta 1 Antibody (OTI1E12) [Janelia Fluor® 549]

CEDLAP
DPD1
latency-associated peptide
TGF beta
TGF beta1
TGFB
TGFB1
TGF-beta 1 protein
TGFbeta 1
TGF-beta 1
TGFbeta
TGF-beta-1
transforming growth factor beta-1
transforming growth factor, beta 1

Background

TGF-beta-1 is a multifunctional cytokine that belongs to a superfamily of structurally related regulatory proteins, which includes three mammalian TGF-beta isoforms (TGF-beta-1, -beta-2, and -beta-3), activin/inhibins and bone morphogenetic proteins. The most abundant isoform, TGF-beta-1, is a 25kDa homodimer composed of two 12.5kDa subunits joined by disulfide bonds. TGF-beta-1 is a highly conserved molecule - the amino acid sequence between human and mouse differ only by one residue. Although originally defined by its ability to cause anchorage independent cell growth and changes in cell morphology of rat fibroblasts, subsequent research has revealed that TGF-beta is actually a major growth inhibitor for most cell types. It is produced by a wide variety of cell and tissue types during all stages of cell differentiation. TGF-beta-1 sources include platelets, bone and soft tissues such as placenta and kidneys.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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TGF-beta 1
Antibody (OTI1E12) [J ...

NBP2-74495JF549

Species: Hu, Mu, Rt

Applications: WB, Flow, ICC/IF

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Product General Protocols

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Video Protocols

WB Video Protocol

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Secondary Antibodies

Isotype Controls

Additional TGF-beta 1 Products

Research Areas for TGF-beta 1 Antibody (NBP2-74495JF549)

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Blogs on TGF-beta 1.

Check out the latest blog posts on TGF-beta 1.

TGF-beta 1 - a versatile signaling molecule with roles in development and disease
The transforming growth factor-beta (TGF-beta) family consists of a wide variety of signaling proteins with roles in development. TGF-beta signaling controls growth, differentiation, and immune responses and is often misregulated in cancer. TGF-beta ... Read full blog post.

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Bioinformatics

Gene Symbol

TGFB1

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At	=	A. thaliana	SyHa	=	Golden Syrian Hamster
All	=	All Species	Ha	=	Hamster
An	=	Animal	Hu	=	Human
ArHa	=	Armenian Hamster	I	=	Insect
Av	=	Avian	Ll	=	Llama
Bb	=	Baboon	Ma	=	Mammal
Ba	=	Bacteria	Mk	=	Monkey
Bv	=	Bovine	Mu	=	Mouse
Ca	=	Canine	Multi	=	Multi-species
Ce	=	C. Elegans	NA	=	Non-species specific
Ch	=	Chicken	Or	=	Orangutan
ChHa	=	Chinese Hamster	Pl	=	Plant
Cm	=	Cynomolgus Monkey	Pm	=	Primate
Do	=	Donkey	Po	=	Porcine
Dr	=	Drosophilia	Rb	=	Rabbit
Ec	=	E. Coli	Rt	=	Rat
Eq	=	Equine	RM	=	Rhesus Macaque
Fe	=	Feline	Sh	=	Sheep
Ft	=	Ferret	Vb	=	Vertebrate
Fi	=	Fish	Vi	=	Virus
Fu	=	Fungi	Xp	=	Xenopus
Ge	=	Gerbil	Ye	=	Yeast
GP	=	Guinea Pig	Ze	=	Zebrafish
Gt	=	Goat

TGF-beta 1 Antibody (OTI1E12) [Janelia Fluor® 549]

Species Glossary

Images

Product Details

Order Details

TGF-beta 1 Antibody (OTI1E12) [Janelia Fluor® 549] Summary

Applications/Dilutions

Reactivity Notes

Packaging, Storage & Formulations

Notes

Alternate Names for TGF-beta 1 Antibody (OTI1E12) [Janelia Fluor® 549]

Background

Limitations

Customers Who Viewed This Item Also Viewed...

Publications for TGF-beta 1 Antibody (NBP2-74495JF549) (0)

Reviews for TGF-beta 1 Antibody (NBP2-74495JF549) (0)

Product General Protocols

Video Protocols

FAQs for TGF-beta 1 Antibody (NBP2-74495JF549) (0)

Secondary Antibodies

Isotype Controls

Additional TGF-beta 1 Products

Research Areas for TGF-beta 1 Antibody (NBP2-74495JF549)

Blogs on TGF-beta 1.

Customers Who Bought This Also Bought

Contact Information

Product PDFs

Calculators

Review this Product

Bioinformatics