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TfR (Transferrin R) Antibody (MEM-189) [DyLight 550]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, Flow, IP, CyTOF-ready
Clone
MEM-189
Clonality
Monoclonal
Host
Mouse
Conjugate
DyLight 550

Order Details

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View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NB500-493AF350
Alexa Fluor 405
NB500-493AF405
Alexa Fluor 488
NB500-493AF488
Alexa Fluor 532
NB500-493AF532
Alexa Fluor 594
NB500-493AF594
Alexa Fluor 647
NB500-493AF647
Alexa Fluor 700
NB500-493AF700
Alexa Fluor 750
NB500-493AF750
Allophycocyanin
NB500-493APC
Allophycocyanin/Cy7
NB500-493APCCY7
Biotin
NB500-493B
CoraFluor 1
NB500-493CL1
DyLight 350
NB500-493UV
DyLight 405
NB500-493V
DyLight 488
NB500-493G
DyLight 594
NB500-493DL594
DyLight 650
NB500-493C
DyLight 680
NB500-493FR
DyLight 755
NB500-493IR
FITC
NB500-493F
HRP
NB500-493H
Janelia Fluor 525
NB500-493JF525
Janelia Fluor 549
NB500-493JF549
Janelia Fluor 646
NB500-493JF646
Janelia Fluor 669
NB500-493JF669
PE
NB500-493PE
PE/Atto594
NB500-493PEATT594
PE/Cy5.5
NB500-493PECY55
PE/Cy7
NB500-493PECY7
PerCP
NB500-493PCP
Unconjugated
NB500-493-0.1mg
mFluor Violet 450 SE
NB500-493MFV450
mFluor Violet 500 SE
NB500-493MFV500
mFluor Violet 610 SE
NB500-493MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
NB500-493-0.1mg
BSA Free
NB500-493-0.1mg
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Datasheet
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Protocols & FAQs
Support & Research

TfR (Transferrin R) Antibody (MEM-189) [DyLight 550] Summary

Additional Information
Clone MEM-189 was used by HLDA to establish CD designation.
Immunogen
KG1 human acute myelogenous leukaemia cell line (NM_001128148.1).
Localization
Cell membrane; Single-pass type II membrane protein. Melanosome (identified by mass spectrometry in melanosome fractions from stage I to stage IV). Transferrin receptor protein 1, serum form: Secreted.
Marker
Recycling Endosome Marker
Specificity
The antibody MEM-189 reacts with CD71 antigen (transferrin receptor), a 95 kDa type II homodimeric transmembrane glycoprotein expressed on activated B and lymphocytes, macrophages and erythroid precursors; it is lost on resting blood leukocytes. The antibody MEM-189 does not block binding of transferrin to the receptor. HLDA VI; WS Code NL N-L025
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
TFRC
Purity
Protein A purified
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Applications/Dilutions

Dilutions
  • CyTOF-ready
  • Flow Cytometry
  • Immunoprecipitation
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A purified

Notes



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for TfR (Transferrin R) Antibody (MEM-189) [DyLight 550]

  • CD71 antigen
  • CD71
  • CD71TRFR
  • p90
  • T9
  • TfR (Transferrin R)
  • TfR (TransferrinR)
  • TfR
  • TFR1
  • TFRC
  • TR
  • transferrin receptor (p90, CD71)
  • transferrin receptor protein 1
  • TRFR

Background

Useful in studies of dividing haematopoietic and tumour cell populations, and metabolic activity.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol TFRC
Entrez
Uniprot