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TCL1B Antibody

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TCL1B was detected in immersion fixed paraffin-embedded sections of human lymphoma using Goat Anti-Human TCL1B Antigen Affinity-purified Polyclonal Antibody (Catalog # AF6794) at 3 µg/mL overnight at 4 °C. Before incubation with the primary antibody, tissue was subjected to heat-induced epitope retrieval using Antigen Retrieval Reagent-Basic (Catalog # CTS013). Tissue was stained using the Anti-Goat HRP-DAB Cell & Tissue Staining Kit (brown; Catalog # CTS008) and counterstained with hematoxylin (blue). Specific staining was localized to cytoplasm. View our protocol for Chromogenic IHC Staining of Paraffin-embedded Tissue Sections.
TCL1B was detected in immersion fixed paraffin-embedded sections of human lymphoma using Goat Anti-Human TCL1B Antigen Affinity-purified Polyclonal Antibody (Catalog # AF6794) at 3 µg/mL overnight at 4 °C. Before ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications IHC
Clonality
Polyclonal
Host
Goat
Conjugate
Unconjugated
Concentration
LYOPH

Order Details

View Available Formulations
Catalog# & Formulation Size Price
Carrier Free
AF6794-SP
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TCL1B Antibody Summary

Immunogen
E. coli-derived recombinant human TCL1B
Ala2-Asp128 (Glu93Arg)
Accession # O95988
Specificity
Detects human TCL1B in direct ELISAs. In direct ELISAs, less than 5% cross-reactivity with recombinant human TCL1A is observed.
Source
N/A
Isotype
IgG
Clonality
Polyclonal
Host
Goat
Gene
TCL1B
Purity Statement
Antigen Affinity-purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
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Applications/Dilutions

Dilutions
  • Immunohistochemistry 5-15 ug/mL

Packaging, Storage & Formulations

Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Preservative
No Preservative
Concentration
LYOPH
Reconstitution Instructions
Sterile PBS to a final concentration of 0.2 mg/mL.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for TCL1B Antibody

  • MTCP1-like protein 1
  • Oncogene TCL1B
  • Oncogene TCL-1B
  • SYN-1
  • Syncytiotrophoblast-specific protein
  • T-cell leukemia/lymphoma 1B
  • T-cell leukemia/lymphoma protein 1B
  • T-cell lymphoma/leukemia 1B
  • TCL1
  • TCL1/MTCP1-like protein 1
  • TCL1B
  • TML1
  • TML1TCL1/ MTCP1-like 1

Background

TCL1B (T cell leukemia protein 1B; also SYN1 and [p15]TML1) is a monomeric,15 kDa (predicted) member of the TCL1 family of proteins. It is expressed in the embryo and syncytiotrophoblast, and interacts with Akt1 and Akt2 kinase, promoting their activation and the subsequent deactivation of proapoptotic molecules. Human TCL1B is 128 amino acids (aa) in length. There is no definitive structural motif that characterizes TCL1B, save for a unique beta -barrel configuration. Full length human TCL1B shares less than 35% aa identity with five orthologous mouse TCL1B isoforms.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol TCL1B
Uniprot