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STAM-1 Antibody (29C678) [FITC]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB
Clone
29C678
Clonality
Monoclonal
Host
Mouse
Conjugate
FITC

Order Details

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STAM-1 Antibody (29C678) [FITC] Summary

Immunogen
This antibody was developed against a synthetic peptide corresponding to amino acids 149-165 of human STAM.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
STAM
Purity
Protein G purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
PBS
Preservative
0.05% Sodium Azide
Purity
Protein G purified

Alternate Names for STAM-1 Antibody (29C678) [FITC]

  • DKFZp686J2352
  • HSE1 Homolog
  • signal transducing adapter molecule 1
  • signal transducing adaptor molecule (SH3 domain and ITAM motif) 1
  • STAM
  • STAM1
  • STAM-1
  • STAM1STAM-1

Background

STAM was identified by the rapid tyrosine-phosphorylation of its product in response to cytokine stimulation. The encoded protein contains a SH3 domain and the immunoreceptor tyrosine-based activation motif (ITAM). This protein associates with JAK3 and JAK2 kinases via its ITAM region, and is phosphorylated by the JAK kinases upon cytokine stimulation, which suggests the function of this protein is as an adaptor molecule involved in the downstream signaling of cytokine receptors. HGS/HRS (hepatocyte grwoth factor-regulated tyrosine kinase substrate) has been found to bind and counteract the function of this protein.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol STAM