Spectrin beta 1 Antibody (4C3)

Spectrin (Sp), the most abundant of the erythrocyte membrane skeleton proteins, helps these cells maintain their characteristic biconcave shape while remaining flexible and elastic. Erythrocyte Sp is a heterodimer composed of a 280 kDa alpha subunit and a 246 kDa beta subunit which associate in a side-to-side, antiparallel configuration to form a 100 nm rod-like structure. Sp in other tissues may be composed of distinct but homologous alpha and beta subunits, sometimes referred to as fodrin. A newly introduced nomenclature designates the Sp subunits of the erythrocyte as alpha-1 and beta-1, and the fodrin subunits as alpha-2 and beta-2. Alternatively spliced forms of each are designated as epsilon-1, epsilon-2, etc. (e.g. beta-1 epsilon-1).

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 2 confirmed species: Human, Canine.

We have publications tested in 2 applications: IHC-Fr, WB.

Showing Publications 1 - 2 of 2.

Publications using NB300-574	Applications	Species
Geiger M, Janes T, Keshavarz H et al. A C-peptide complex with albumin and Zn2+ increases measurable GLUT1 levels in membranes of human red blood cells Sci Rep 2020-10-15 [PMID: 33060722] (WB, Human)	WB	Human
Martin PT, Golden B, Okerblom J et al. A Comparative Study of N-glycolylneuraminic Acid (Neu5Gc) and Cytotoxic T Cell (CT) Carbohydrate Expression in Normal and Dystrophin-Deficient Dog and Human Skeletal Muscle. PLoS ONE 2014-02-07 [PMID: 24505439] (IHC-Fr, Canine)	IHC-Fr	Canine

Array NB300-574

• Spectrin beta 1 Antibodies
• Spectrin beta 1 Proteins