SLC12A3 Antibody

Images

 
Orthogonal Strategies: Immunohistochemistry-Paraffin: SLC12A3 Antibody [NBP1-86376] - Analysis in human kidney and liver tissues using NBP1-86376 antibody. Corresponding SLC12A3 RNA-seq data are presented for the ...read more
Immunohistochemistry-Paraffin: SLC12A3 Antibody [NBP1-86376] - Staining of human pancreas shows no positivity in exocrine glandular cells as expected.
Immunohistochemistry-Paraffin: SLC12A3 Antibody [NBP1-86376] - Staining of human kidney shows high expression.
Immunohistochemistry-Paraffin: SLC12A3 Antibody [NBP1-86376] - Staining of human skeletal muscle shows no positivity in myocytes as expected.
Immunohistochemistry-Paraffin: SLC12A3 Antibody [NBP1-86376] - Staining of human liver shows no positivity in hepatocytes as expected.

Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Validated by:
       

Orthogonal Strategies

 

Order Details

SLC12A3 Antibody Summary

Immunogen
This antibody was developed against Recombinant Protein corresponding to amino acids: LLIPYLLGRKRRWSKCKIRVFVGGQINRMDQERKAIISLLSKFRLGFHEVHILPDINQNPRAEHTKRFEDMIAPFRLNDGFKDEATVNEMRRDCPWKISDEEITKNRVKSLRQVRLNEIVLDYSRDAALIVITLPIGRKGKCPSS
Predicted Species
Mouse (90%), Rat (90%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
SLC12A3
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:200 - 1:500
  • Immunohistochemistry-Paraffin 1:200 - 1:500
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Control Peptide
SLC12A3 Protein (NBP1-86376PEP)
Publications
Read Publication using NBP1-86376.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for SLC12A3 Antibody

  • FLJ96318
  • Na-Cl symporter
  • NCC
  • NCCT
  • SLC12A3
  • solute carrier family 12 (sodium/chloride transporters), member 3
  • solute carrier family 12 member 3
  • thiazide-sensitive Na-Cl cotransporter
  • Thiazide-sensitive sodium-chloride cotransporter
  • TSC
  • TSCNaCl electroneutral thiazide-sensitive cotransporter

Background

The SLC12A3 gene encodes a renal thiazide-sensitive sodium-chloride cotransporter that is important for electrolyte homeostasis. This cotransporter mediates sodium and chloride reabsorption in the distal convoluted tubule. Mutations in this gene cause Gitelman s

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for SLC12A3 Antibody (NBP1-86376)(1)

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol SLC12A3