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SHP-2/PTPN11 Antibody (OTI3F2)

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Western Blot: PTPN11/SHP2 Antibody (3F2) [NBP2-03063] Analysis of extracts (35ug) from 9 different cell lines by using anti-PTPN11/SHP2 monoclonal antibody.
Western Blot: PTPN11/SHP2 Antibody (3F2) [NBP2-03063] Analysis of extracts (35ug) from 9 different cell lines by using anti-PTPN11/SHP2 monoclonal antibody.
Flow Cytometry: PTPN11/SHP2 Antibody (3F2) [NBP2-03063] - Analysis of Jurkat cells, using anti-PTPN11/SHP2 antibody, (Red), compared to a nonspecific negative control antibody (Blue).
Western Blot: PTPN11/SHP2 Antibody (3F2) [NBP2-03063] - HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY PTPN11/SHP2 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of ...read more
Flow Cytometry: PTPN11/SHP2 Antibody (3F2) [NBP2-03063] - Analysis of Hela cells, using anti-PTPN11/SHP2 antibody, (Red), compared to a nonspecific negative control antibody (Blue).

Product Details

Summary
Reactivity Hu, Mu, Rt, CaSpecies Glossary
Applications WB, Flow
Clone
OTI3F2
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Concentration
0.99 mg/ml

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NBP2-74173AF350
Alexa Fluor 405
NBP2-74173AF405
Alexa Fluor 488
NBP2-74173AF488
Alexa Fluor 532
NBP2-74173AF532
Alexa Fluor 594
NBP2-74173AF594
Alexa Fluor 647
NBP2-74173AF647
Alexa Fluor 700
NBP2-74173AF700
Alexa Fluor 750
NBP2-74173AF750
Allophycocyanin
NBP2-74173APC
Biotin
NBP2-74173B
CoraFluor 1
NBP2-74173CL1
DyLight 350
NBP2-74173UV
DyLight 405
NBP2-74173V
DyLight 488
NBP2-74173G
DyLight 550
NBP2-74173R
DyLight 594
NBP2-74173DL594
DyLight 650
NBP2-74173C
DyLight 680
NBP2-74173FR
DyLight 755
NBP2-74173IR
FITC
NBP2-74173F
HRP
NBP2-74173H
Janelia Fluor 525
NBP2-74173JF525
Janelia Fluor 549
NBP2-74173JF549
Janelia Fluor 646
NBP2-74173JF646
Janelia Fluor 669
NBP2-74173JF669
PE
NBP2-74173PE
PerCP
NBP2-74173PCP
mFluor Violet 450 SE
NBP2-74173MFV450
mFluor Violet 500 SE
NBP2-74173MFV500
mFluor Violet 610 SE
NBP2-74173MFV610
View Available Formulations
Catalog# & Formulation Size Price
Azide and BSA Free
NBP2-74173
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SHP-2/PTPN11 Antibody (OTI3F2) Summary

Immunogen
Full length human recombinant protein of human PTPN11(NP_002825) produced in HEK293T cell.
Isotype
IgG2a
Clonality
Monoclonal
Host
Mouse
Gene
PTPN11
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Flow Cytometry 1:100
  • Western Blot 1:500-2000
Theoretical MW
67.8 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.3), 1.0% BSA and 50% Glycerol
Preservative
0.02% Sodium Azide
Concentration
0.99 mg/ml
Purity
Immunogen affinity purified

Alternate Names for SHP-2/PTPN11 Antibody (OTI3F2)

  • BPTP3
  • EC 3.1.3.48
  • MGC14433
  • protein tyrosine phosphatase, non-receptor type 11
  • protein tyrosine phosphatase-2
  • Protein-tyrosine phosphatase 1D
  • Protein-tyrosine phosphatase 2C
  • PTP1D
  • PTP-1D
  • PTP2C
  • PTP-2C
  • PTP2CNS1
  • PTPN11
  • SHP2
  • SHP-2
  • SHP2CFC
  • SHPTP2
  • SH-PTP2
  • SH-PTP2Noonan syndrome 1
  • SH-PTP3
  • tyrosine-protein phosphatase non-receptor type 11

Background

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains two tandem Src homology-2 domains, which function as phospho-tyrosine binding domains and mediate the interaction of this PTP with its substrates. This PTP is widely expressed in most tissues and plays a regulatory role in various cell signaling events that are important for a diversity of cell functions, such as mitogenic activation, metabolic control, transcription regulation, and cell migration. Mutations in this gene are a cause of Noonan syndrome as well as acute myeloid leukemia. [provided by RefSeq].

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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SHP-2/PTPN11
Antibody (OTI3F2)
NBP2-03063
SHP-2/PTPN11 Antibody (OTI3F2)
Species: Hu, Mu, Rt, Ca
Applications: WB, Flow

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Bioinformatics

Gene Symbol PTPN11
Entrez