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SH2D1A Antibody (S09-5F6)

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Western Blot: SH2D1A Antibody (S09-5F6) [NBP3-19771] - Western blot detection of SH2D1A in MCF7, C6 cell lysates using NBP3-19771 (1:1000 diluted). Predicted band size: 14KDa. Observed band size: 14KDa.
Western Blot: SH2D1A Antibody (S09-5F6) [NBP3-19771] - Western blot detection of SH2D1A in MCF7, C6 cell lysates using NBP3-19771 (1:1000 diluted). Predicted band size: 14KDa. Observed band size: 14KDa.

Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB
Clone
S09-5F6
Clonality
Monoclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
0.3 mg/ml

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SH2D1A Antibody (S09-5F6) Summary

Additional Information
Recombinant Monoclonal Antibody
Immunogen
A synthetic peptide of human SH2D1A (Uniprot # O60880)
Isotype
IgG
Clonality
Monoclonal
Host
Rabbit
Gene
SH2D1A
Purity
Affinity purified
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Applications/Dilutions

Dilutions
  • Western Blot 1/1000-1/2000
Theoretical MW
14 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.05% BSA
Preservative
0.01% Sodium Azide
Concentration
0.3 mg/ml
Purity
Affinity purified

Alternate Names for SH2D1A Antibody (S09-5F6)

  • DSHP
  • DSHPLYP
  • Duncan disease SH2-protein
  • EBVS
  • FLJ92177
  • IMD5
  • LYP
  • MTCP1
  • SAP/SH2D1A
  • SAPlymphoproliferative syndrome
  • SH2 domain containing 1A
  • SH2 domain-containing protein 1A
  • SH2D1A
  • signaling lymphocyte activation molecule-associated protein
  • Signaling lymphocytic activation molecule-associated protein
  • SLAM associated protein/SH2 domain protein 1A
  • SLAM-associated protein
  • T cell signal transduction molecule SAP
  • T-cell signal transduction molecule SAP
  • XLP
  • XLPD
  • XLPDFLJ18687
  • XLPSH2 domain protein 1A

Background

The cytoplasmic protein encoded by the SH2D1A gene plays an essential role in controlling EBV infection. It is expressed in T and NK cells, but not in B cells or in granulocytes. SH2D1A is expressed at a high level in thymus and lung, with a lower level of expression in spleen and liver. Defects in SH2D1A are a cause of X-linked lymphoproliferative disease (XLPD)also known as Duncan disease. XLPD is characterized by an immunodeficiency following Epstein-Barr virus (EBV)infection. Symptoms include fatal mononucleosis, hypogammaglobulinemia, pancytopenia or malignant lymphoma.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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SH2D1A Antibody
(S09-5F6)
NBP3-19771
SH2D1A Antibody (S09-5F6)
Species: Hu, Mu, Rt
Applications: WB

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol SH2D1A