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SGK1 Antibody [DyLight 350]

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Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, ELISA, ICC/IF, IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
DyLight 350

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NBP1-76578AF350
Alexa Fluor 405
NBP1-76578AF405
Alexa Fluor 488
NBP1-76578AF488
Alexa Fluor 532
NBP1-76578AF532
Alexa Fluor 594
NBP1-76578AF594
Alexa Fluor 647
NBP1-76578AF647
Alexa Fluor 700
NBP1-76578AF700
Alexa Fluor 750
NBP1-76578AF750
Biotin
NBP1-76578B
CoraFluor 1
NBP1-76578CL1
DyLight 405
NBP1-76578V
DyLight 488
NBP1-76578G
DyLight 550
NBP1-76578R
DyLight 594
NBP1-76578DL594
DyLight 650
NBP1-76578C
DyLight 680
NBP1-76578FR
DyLight 755
NBP1-76578IR
FITC
NBP1-76578F
HRP
NBP1-76578H
Janelia Fluor 525
NBP1-76578JF525
Janelia Fluor 549
NBP1-76578JF549
Janelia Fluor 585
NBP1-76578JF585
Janelia Fluor 635
NBP1-76578JF635
Janelia Fluor 646
NBP1-76578JF646
Janelia Fluor 669
NBP1-76578JF669
PerCP
NBP1-76578PCP
Unconjugated
NBP1-76578
mFluor Violet 450 SE
NBP1-76578MFV450
mFluor Violet 500 SE
NBP1-76578MFV500
mFluor Violet 610 SE
NBP1-76578MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
NBP1-76578
BSA Free
NBP1-76578
BSA Free
NBP1-76578-0.025mg
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SGK1 Antibody [DyLight 350] Summary

Immunogen
Antibody was raised against an 18 amino acid synthetic peptide near the carboxy terminus of human SGK1. The immunogen is located within amino acids 370 - 420 of SGK1. Amino Acid Squence: PNDLRHFDPEFTEEPPVPN
Specificity
SGK1 antibody is predicted to not cross-react with other SGK protein family members. At least five isoforms are known to exist
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
SGK1
Purity
Peptide affinity purified
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Applications/Dilutions

Dilutions
  • ELISA
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Bovine (89%), Chicken (84%), Rabbit (89%)

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Peptide affinity purified

Notes



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for SGK1 Antibody [DyLight 350]

  • EC 2.7.11
  • EC 2.7.11.1
  • serine/threonine protein kinase SGK
  • serine/threonine-protein kinase Sgk1
  • serum/glucocorticoid regulated kinase 1
  • serum/glucocorticoid regulated kinase
  • Serum/glucocorticoid-regulated kinase 1
  • SGK
  • SGK1

Background

SGK1 encodes a serine/threonine protein kinase that is highly similar to the rat serum-and glucocorticoid-induced protein kinase (SGK). This gene was identified in a screen of hepatocellular genes regulated in response to cellular hydration or swelling. Cellular hydration is a catabolic signal, stimulating glycogenolysis and proteolysis, and inhibiting protein and glycogen synthesis. This kinase has been shown to be important in activating certain potassium, sodium, and chloride channels. Expression of this gene in hepatocytes is stimulated by transforming growth factor-beta (TGF-beta) which participates in the pathophysiology of diabetic complications. Since both TGF-beta expression and SGK expression are elevated in diabetic nephropathy, this suggests an involvement of SGK in the development of this condition.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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SGK1 Antibody
[DyLight 350]
NBP1-76578UV
SGK1 Antibody [DyLight 350]
Species: Hu, Mu, Rt
Applications: WB, ELISA, ICC/IF, IHC

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Product General Protocols

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Video Protocols

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Bioinformatics

Gene Symbol SGK1