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Serpin A7/TBG Antibody

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Western Blot: Serpin A7/TBG Antibody [NBP1-32963] - Sample (30 ug of whole cell lysate) A: Hela 10% SDS PAGE; antibody diluted at 1:1000.
Western Blot: Serpin A7/TBG Antibody [NBP1-32963] - Sample (30 ug of whole cell lysate) A: Hela 10% SDS PAGE; antibody diluted at 1:1000.
Immunocytochemistry/ Immunofluorescence: Serpin A7/TBG Antibody [NBP1-32963] - Analysis of Thyroxine Binding Globulin on HeLa, using NBP1-32963.
Immunohistochemistry-Paraffin: Serpin A7/TBG Antibody [NBP1-32963] - Paraffin-embedded hepatoma; antibody dilution 1:500.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ICC/IF, IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

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Serpin A7/TBG Antibody Summary

Immunogen
Recombinant protein encompassing a sequence within the center region of human Serpin A7/TBG. The exact sequence is proprietary.
Localization
Secreted
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
SERPINA7
Purity
Antigen Affinity-purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Immunocytochemistry/ Immunofluorescence 1:100-1:1000
  • Immunohistochemistry 10 - 1:500
  • Immunohistochemistry-Paraffin 1:100-1:1000
  • Western Blot 1:500-1:3000

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
0.1M Tris (pH 7), 0.1M Glycine, 10% Glycerol
Preservative
0.01% Thimerosal
Purity
Antigen Affinity-purified

Alternate Names for Serpin A7/TBG Antibody

  • antitrypsin), member 7
  • FLJ17820
  • member 7
  • Serpin A7
  • serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin)
  • T4-binding globulin
  • TBG
  • TBGclade A (alpha-1 antiproteinase
  • thyroxin-binding globulin
  • thyroxine-binding globulin

Background

Thyroxine Binding Globulin (TBG) is one of three proteins responsible for carrying the thyroid hormones thyroxine (T4) and 3,5,3 triiodothyronine (T3) in the bloodstream, along with transthyretin and albumin. TBG has the highest affinity for T4 and T3, but is present in the lowest concentration of the three proteins. Despite its low concentration, TBG carries the majority of T4 in serum. Due to the very low serum concentration of T4 & T3, TBG is rarely more than 25% saturated with ligand. Unlike transthyretin and albumin, TBG has a single binding site for T4/T3. Genomically, TBG is a serpin, although it has no inhibitory function like many other members of this class of proteins. TBG is synthesized primarily in the liver.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Serpin A7/TBG
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NBP1-32963
Serpin A7/TBG Antibody
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Applications: WB, ICC/IF, IHC
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

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Bioinformatics

Gene Symbol SERPINA7