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Seladin 1 Antibody [Janelia Fluor® 525]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Janelia Fluor 525

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NBP2-98505AF350
Alexa Fluor 405
NBP2-98505AF405
Alexa Fluor 488
NBP2-98505AF488
Alexa Fluor 532
NBP2-98505AF532
Alexa Fluor 594
NBP2-98505AF594
Alexa Fluor 647
NBP2-98505AF647
Alexa Fluor 700
NBP2-98505AF700
Alexa Fluor 750
NBP2-98505AF750
Allophycocyanin
NBP2-98505APC
Biotin
NBP2-98505B
CoraFluor 1
NBP2-98505CL1
DyLight 350
NBP2-98505UV
DyLight 405
NBP2-98505V
DyLight 488
NBP2-98505G
DyLight 550
NBP2-98505R
DyLight 594
NBP2-98505DL594
DyLight 650
NBP2-98505C
DyLight 680
NBP2-98505FR
DyLight 755
NBP2-98505IR
FITC
NBP2-98505F
HRP
NBP2-98505H
Janelia Fluor 549
NBP2-98505JF549
Janelia Fluor 585
NBP2-98505JF585
Janelia Fluor 635
NBP2-98505JF635
Janelia Fluor 646
NBP2-98505JF646
Janelia Fluor 669
NBP2-98505JF669
PE
NBP2-98505PE
PerCP
NBP2-98505PCP
Unconjugated
NBP2-98505-100ul
mFluor Violet 450 SE
NBP2-98505MFV450
mFluor Violet 500 SE
NBP2-98505MFV500
mFluor Violet 610 SE
NBP2-98505MFV610
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Seladin 1 Antibody [Janelia Fluor® 525] Summary

Immunogen
Produced in rabbits immunized with E. coli-derived Human Seladin 1 fragment.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
DHCR24
Purity
Antigen and protein A Affinity-purified
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Applications/Dilutions

Dilutions
  • Immunohistochemistry-Paraffin
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Antigen and protein A Affinity-purified

Notes



Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for Seladin 1 Antibody [Janelia Fluor® 525]

  • 24-dehydrocholesterol reductaseNbla03646
  • DCE
  • desmosterol-to-cholesterol enzyme
  • Diminuto/dwarf1 homolog
  • EC 1.3.1.72
  • KIAA0018SELADIN1
  • seladin 1,3-beta-hydroxysterol delta-24-reductase
  • seladin-1
  • selective AD indicator 1,3 beta-hydroxysterol delta 24-reductase

Background

Seladin 1 encodes a flavin adenine dinucleotide (FAD)-dependent oxidoreductase which catalyzes the reduction of the delta-24 double bond of sterol intermediates during cholesterol biosynthesis. The protein contains a leader sequence that directs it to the endoplasmic reticulum membrane. Missense mutations in this gene have been associated with desmosterolosis. Also, reduced expression of the gene occurs in the temporal cortex of Alzheimer disease patients and overexpression has been observed in adrenal gland cancer cells.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol DHCR24