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SCP1 Antibody [Janelia Fluor® 549]

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Product Details

Summary
Reactivity Mu, Rt, Ch, Ma, Pa, Pm, Hu(-)Species Glossary
Applications WB, Simple Western, ChIP, ICC/IF, IHC, IP, ChIP
Clonality
Polyclonal
Host
Rabbit
Conjugate
Janelia Fluor 549

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SCP1 Antibody [Janelia Fluor® 549] Summary

Immunogen
A synthetic peptide made to the C-terminus of the mouse SCP1 protein sequence. [UniProt# Q62209]
Localization
Nuclear
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
SYCP1
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Chromatin Immunoprecipitation (ChIP)
  • Chromatin Immunoprecipitation
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry
  • Immunohistochemistry-Frozen
  • Immunohistochemistry-Paraffin
  • Immunoprecipitation
  • Simple Western
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

Mammal reactivity reported in scientific literature (PMID: 25981592). Parasite reactivity reported in scientific literature (PMID: 27084479). Chicken reactivity reported in scientific literature (PMID: 28174243). Use in Monkey reported in scientific literature (PMID: 31907447). This antibody has not been shown to have human reactivity.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Immunogen affinity purified

Notes

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for SCP1 Antibody [Janelia Fluor® 549]

  • Cancer/testis antigen 8
  • CT8MGC104417
  • HOM-TES-14
  • SCP1SCP-1
  • synaptonemal complex protein 1

Background

The synaptonemal complex is a multiprotein complex that mediates synapses during the zygotene stage and then disintegrates. Resulting from chromosome pairing interactions, the synaptonemal complex unites homologous chromosomes during the prophase stage of meiosis.

Synaptonemal complex protein 1 (SCP1) is a major component of the transverse filaments of synaptonemal complex. SCP1 is therefore critical to proper homologus chromosome pairing.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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NB300-229JF549
Species: Mu, Rt, Ch, Ma, Pa, Pm, Hu(-)
Applications: WB, Simple Western, ChIP, ICC/IF, IHC, IP, ChIP

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Product General Protocols

Video Protocols

WB Video Protocol
ChIP Video Protocol
ChIP Webinar
ICC/IF Video Protocol

FAQs for SCP1 Antibody (NB300-229JF549) (0)

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Secondary Antibodies

 

Isotype Controls

Additional SCP1 Products

Array NB300-229JF549

Research Areas for SCP1 Antibody (NB300-229JF549)

Find related products by research area.

Blogs on SCP1.

Using SCP3/SYCP3 Antibodies as Meiosis Markers in Gametogenesis and DNA Repair Studies
The synaptonemal complex (SC) is a protein structure that forms during the synapsis of homologous chromosomes during meiosis. This structure is involved in the processes of chromosome synapsis, genetic recombination and subsequent chromosome segregati...  Read full blog post.

SCP1 a Potential Cancer Target for Immunotherapy
Synaptonemal Complex Protein 1 (SCP1) is a novel tumor antigen that belongs to the growing family of cancer/testis antigens (CTA). SCP-1 is known to be selectively expressed during the meiotic prophase of spermatocytes and is involved in the pairing o...  Read full blog post.

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Bioinformatics

Gene Symbol SYCP1