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S1P5/EDG-8 Antibody (282503) [Janelia Fluor® 549]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow, CyTOF-ready
Clone
282503
Clonality
Monoclonal
Host
Mouse
Conjugate
Janelia Fluor 549

Order Details

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S1P5/EDG-8 Antibody (282503) [Janelia Fluor® 549] Summary

Immunogen
BaF3 mouse pro-B cell line transfected with human S1P5/EDG‑8
Met1-Asp398
Accession # Q9H228
Specificity
Detects human S1P5/EDG‑8. Stains human S1P5/EDG‑8 transfectants but not irrelevant transfectants.
Isotype
IgG2b
Clonality
Monoclonal
Host
Mouse
Gene
S1PR5
Purity
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • CyTOF-ready
  • Flow Cytometry
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified from hybridoma culture supernatant

Notes

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for S1P5/EDG-8 Antibody (282503) [Janelia Fluor® 549]

  • EDG8
  • Edg-8
  • EDG8S1P receptor Edg-8
  • Endothelial differentiation G-protein-coupled receptor 8
  • endothelial differentiation, sphingolipid G-protein-coupled receptor, 8
  • LPB4
  • S1P receptor 5
  • S1P5
  • S1PR5
  • sphingosine 1-phosphate receptor 5
  • sphingosine 1-phosphate receptor EDG8
  • Sphingosine 1-phosphate receptor Edg-8
  • sphingosine-1-phosphate receptor 5
  • SPPR-1
  • SPPR-2

Background

Edg8 is a Lysophospholipid/Lysosphingolipid Receptor activated by sphingosine-1-phosphate. Two differently expressed splice variants, 2.4 kb and 5.4 kb, are produced by alternative splicing. Edg8 has been reported in rat brain, lung, small intestine, spinal cord, and spleen. ESTs have been isolated from human cancer libraries of the head/neck and skin, as well as mouse brain and liver libraries. Caution: The rat EDG-8 gene has also been described as NRG-1, but should not be confused with the neuregulin-1 gene whose approved symbol is NRG-1.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol S1PR5