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RSK1 [p Ser380] Antibody (1024F) [DyLight 405]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ICC/IF, ICC/IF
Clone
1024F
Clonality
Monoclonal
Host
Rabbit
Conjugate
DyLight 405

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
MAB79672AF350
Alexa Fluor 405
MAB79672AF405
Alexa Fluor 488
MAB79672AF488
Alexa Fluor 532
MAB79672AF532
Alexa Fluor 594
MAB79672AF594
Alexa Fluor 647
MAB79672AF647
Alexa Fluor 700
MAB79672AF700
Alexa Fluor 750
MAB79672AF750
Biotin
MAB79672B
DyLight 350
MAB79672UV
DyLight 488
MAB79672G
DyLight 550
MAB79672R
DyLight 594
MAB79672DL594
DyLight 650
MAB79672C
DyLight 680
MAB79672FR
DyLight 755
MAB79672IR
FITC
MAB79672F
HRP
MAB79672H
Janelia Fluor 549
MAB79672JF549
Janelia Fluor 646
MAB79672JF646
Unconjugated
MAB79672
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
MAB79672
Azide and BSA Free
MAB79672
Azide and BSA Free
MAB79672-SP
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RSK1 [p Ser380] Antibody (1024F) [DyLight 405] Summary

Additional Information
Recombinant Monoclonal Antibody.
Immunogen
Phosphopeptide containing the human RSK1 S380 site
Accession # Q15418
Modification
p Ser380
Isotype
IgG
Clonality
Monoclonal
Host
Rabbit
Gene
RPS6KA1
Purity
Protein A or G purified
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Applications/Dilutions

Dilutions
  • Immunocytochemistry
  • Immunocytochemistry/ Immunofluorescence
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified

Notes



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for RSK1 [p Ser380] Antibody (1024F) [DyLight 405]

  • 90kD, polypeptide 1)
  • EC 2.7.11
  • EC 2.7.11.1,90 kDa ribosomal protein S6 kinase 1
  • HU-1
  • MAP kinase-activated protein kinase 1a
  • MAPK-activated protein kinase 1a
  • MAPKAP kinase 1a
  • MAPKAPK-1a
  • MAPKAPL1A
  • p90RSK1
  • p90S6K
  • ribosomal protein S6 kinase alpha 1
  • ribosomal protein S6 kinase alpha-1
  • ribosomal protein S6 kinase, 90kD, polypeptide 1
  • ribosomal protein S6 kinase, 90kDa, polypeptide 1
  • Ribosomal S6 kinase 1
  • RPS6KA1
  • RSK
  • RSK1
  • RSK-1
  • RSK1p90-RSK 1
  • S6K-alpha 1
  • S6K-alpha-1

Background

Rsk-1 (p90-Rsk-1) is a member of a family of 90 kDa ribosomal protein S6 kinases, which includes Rsk-1, Rsk-2 and Rsk-3. These are broadly expressed serine/threonine protein kinases (1) activated in response to mitogenic stimuli, including extracellular signal-regulated protein kinases Erk1 and Erk2 (2). p90-Rsk-1 is activated by MAPK in vitro and in vivo via phosphorylation (3). Active Rsks appear to play a major role in transcriptional regulation by translocating to the nucleus and phosphorylating c-Fos and CREB (2,4).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol RPS6KA1