RelA/NFkB p65 [p Ser536] Antibody (1091B) [Unconjugated]

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

RelA belongs to a family of transcription factors, NF kappa B (Nuclear Factor kappa from B cells) complex, that play a fundamental role in inflammatory and immune responses. The NF kappa B complex is composed of a heterodimer of a Rel family member (RelA, c-Rel, RelB) and either NF kappa B1 or NF kappa B2 subunits. RelA and NF kappa B1 are the most common heterodimeric pair. The NF kappa B complex is sequestered in the cytoplasm by inhibitory I kappa B proteins. Upon cellular activation, the ubiquitin-proteosome pathway degrades the I kappa B proteins allowing the NF kappa B complex to translocate to the nucleus and activate gene transcription.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 2 confirmed species: Human, Mouse.

We have publications tested in 2 applications: ICC, Western Blot.

Showing Publications 1 - 8 of 8.

Publications using MAB72261	Applications	Species
Suehiro, JI;Kimura, T;Fukutomi, T;Naito, H;Kanki, Y;Wada, Y;Kubota, Y;Takakura, N;Sakurai, H; Endothelial specific LAT1 ablation normalizes tumor vasculature JCI insight 2024-08-20 [PMID: 39163136] (Western Blot, Human)	Western Blot	Human
Dib S, Loiola RA, Sevin E et al. TNF? Activates the Liver X Receptor Signaling Pathway and Promotes Cholesterol Efflux from Human Brain Pericytes Independently of ABCA1 International journal of molecular sciences 2023-03-22 [PMID: 36983062]
Dib S, Loiola RA, Sevin E et al. TNF? Activates the Liver X Receptor Signaling Pathway and Promotes Cholesterol Efflux from Human Brain Pericytes Independently of ABCA1 International journal of molecular sciences 3/22/2023 [PMID: 36983062]
M Tabarsa, S You, K Yelithao, S Palanisamy, NM Prabhu, M Nan Isolation, structural elucidation and immuno-stimulatory properties of polysaccharides from Cuminum cyminum Carbohydr Polym, 2019-11-18;230(0):115636. 2019-11-18 [PMID: 31887877] (Western Blot, Mouse)	Western Blot	Mouse
Ewelina Majewska, Javier Márquez, Jan Albrecht, Monika Szeliga Transfection with GLS2 Glutaminase (GAB) Sensitizes Human Glioblastoma Cell Lines to Oxidative Stress by a Common Mechanism Involving Suppression of the PI3K/AKT Pathway Cancers (Basel) 1/19/2019 [PMID: 30669455]
L Gao, W Zhang, WQ Zhong, ZJ Liu, HM Li, ZL Yu, YF Zhao Tumor associated macrophages induce epithelial to mesenchymal transition via the EGFR/ERK1/2 pathway in head and neck squamous cell carcinoma Oncol. Rep., 2018-08-17;40(5):2558-2572. 2018-08-17 [PMID: 30132555] (Western Blot, Human)	Western Blot	Human
Li Y, Shen S, Ding S, Wang L. Toll-like receptor 2 downregulates the cholesterol efflux by activating the nuclear factor‑kappa B pathway in macrophages and may be a potential therapeutic target for the prevention of atherosclerosis Experimental and Therapeutic Medicine 10/31/2017 [PMID: 29375683]
R El-Amine, D Germini, VV Zakharova, T Tsfasman, EV Sheval, RAN Louzada, C Dupuy, C Bilhou-Nab, A Hamade, F Najjar, E Oksenhendl, M Lipinski, BV Chernyak, YS Vassetzky HIV-1 Tat protein induces DNA damage in human peripheral blood B-lymphocytes via mitochondrial ROS production Redox Biol, 2017-12-07;15(0):97-108. 2017-12-07 [PMID: 29220699] (ICC, Western Blot, Human)	ICC, Western Blot	Human

Array MAB72261

• RelA/NFkB p65 Antibodies
• RelA/NFkB p65 Antibody Pack
• RelA/NFkB p65 ELISA Kits
• RelA/NFkB p65 Inhibitors
• RelA/NFkB p65 Kit
• RelA/NFkB p65 Lysate
• RelA/NFkB p65 Proteins