Recombinant Human Angiopoietin-1 Protein, CF

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Angiopoietin-1 (Ang-1) is a secreted glycoprotein that plays a critical role in the development and maintenance of the vascular system (1, 2). It contains a coiled-coil region and a C-terminal fibrinogen-like domain separated by a short flexible region (3, 4). Mature human Angiopoietin-1 shares 97% amino acid sequence identity with mouse and rat Angiopoietin-1. It is expressed by vascular smooth muscle cells and pericytes as an approximately 70 kDa molecule that associates into
disulfide-linked homotrimers, tetramers, and pentamers (3, 5). Angiopoietin-1 binds and activates the receptor tyrosine kinase Tie-2, and its association into tetramers is important for full Tie-2 activation (3, 4). Angiopoietin-1 ligation of Tie-2 on vascular endothelial cells (EC) induces the development and branching of blood vessels (6, 7). In sub-confluent EC (i.e. during angiogenesis), Angiopoietin-1 promotes EC motility and Tie-2 localization at the trailing edge of the cell (8). In confluent EC (i.e. in homeostasis), multimeric Angiopoietin-1 enhances vascular integrity by promoting the in trans homotypic association of Tie-2 between EC or with the substratum (8, 9). In addition, Angiopoietin-1 suppresses several VEGF-induced effects on the vasculature including endothelial permeability, stretch-induced release of Angiopoietin-2, and up-regulation of the leukocyte adhesion molecules VCAM-1, ICAM-1, and E-Selectin (10-12). Angiopoietin-1 also interacts with a variety of integrins and the extracellular matrix independently of Tie-2 (13, 14). These interactions support the adhesion, migration and stress resistance of EC, fibroblasts, and myocytes (13, 14). Angiopoietin-1 can protect against pulmonary arterial hypertension (5), reduce the extent of fibrosis and remodeling in infarcted diabetic myocardium (15), and enhance tumor progression and metastasis (16).

We have publications tested in 4 confirmed species: Human, Mouse, Rat, Bovine.

We have publications tested in 8 applications: Bioassay, Cell Culture, Control, ELISA (Capture), ELISA (Standard), In Vivo, Surface Plasmon Resonance, Western Blot.

Showing Publications 1 - 10 of 68. Show All 68 Publications. Collapse Publications.

Publications using 923-AN/CF	Applications	Species
E Lee, EA Lee, E Kong, H Chon, M Llaiqui-Co, CH Park, BY Park, NR Kang, JS Yoo, HS Lee, HS Kim, SH Park, SW Choi, D Vestweber, JH Lee, P Kim, WS Lee, I Kim An agonistic anti-Tie2 antibody suppresses the normal-to-tumor vascular transition in the glioblastoma invasion zone Experimental & Molecular Medicine, 2023-02-24;55(2):470-484. 2023-02-24 [PMID: 36828931] (Bioassay, Human)	Bioassay	Human
H Lu, P Yuan, X Ma, X Jiang, S Liu, C Ma, S Philipsen, Q Zhang, J Yang, F Xu, C Zhang, Y Zhang, W Zhang Angiotensin-converting enzyme inhibitor promotes angiogenesis through Sp1/Sp3-mediated inhibition of notch signaling in male mice Nature Communications, 2023-02-09;14(1):731. 2023-02-09 [PMID: 36759621] (Bioassay, Human)	Bioassay	Human
S Tan, Y Chen, S Du, W Li, P Liu, J Zhao, P Yang, J Cai, R Gao, Z Wang TIE2-high cervical cancer cells promote tumor angiogenesis by upregulating TIE2 and VEGFR2 in endothelial cells Translational Oncology, 2022-09-15;26(0):101539. 2022-09-15 [PMID: 36116242] (Bioassay, Human)	Bioassay	Human
H Zhou, T Chen, Y Li, J You, X Deng, N Chen, T Li, Y Zheng, R Li, M Luo, J Wu, L Wang Glycation of Tie-2 Inhibits Angiopoietin-1 Signaling Activation and Angiopoietin-1-Induced Angiogenesis International Journal of Molecular Sciences, 2022-06-27;23(13):. 2022-06-27 [PMID: 35806141] (Bioassay, Human)	Bioassay	Human
LT Hsieh, SJ Dos Santos, BS Hall, J Ogbechi, AD Loglo, FJ Salguero, MT Ruf, G Pluschke, RE Simmonds Aberrant stromal tissue factor localisation and mycolactone-driven vascular dysfunction, exacerbated by IL-1beta, are linked to fibrin formation in Buruli ulcer lesions PloS Pathogens, 2022-01-31;18(1):e1010280. 2022-01-31 [PMID: 35100311] (Bioassay, Human)	Bioassay	Human
T Shimazaki, N Noro, K Hagikura, T Matsumoto, C Yoshida-No Quantitative Analysis of Factors Regulating Angiogenesis for Stem Cell Therapy Biology, 2021-11-20;10(11):. 2021-11-20 [PMID: 34827205] (Bioassay, Human)	Bioassay	Human
R Luck, A Karakatsan, B Shah, G Schermann, H Adler, J Kupke, N Tisch, HW Jeong, MK Back, F Hetsch, A D'Errico, M De Palma, E Wiedtke, D Grimm, A Acker-Palm, J von Engelh, RH Adams, HG Augustin, C Ruiz de Al The angiopoietin-Tie2 pathway regulates Purkinje cell dendritic morphogenesis in a cell-autonomous manner Cell Reports, 2021-08-17;36(7):109522. 2021-08-17 [PMID: 34407407] (Bioassay, Mouse)	Bioassay	Mouse
Y Koya, H Nara, S Yagi, C Ueno, M Kamohara An engineered tetra-valent antibody fully activates the Tie2 receptor with comparable potency to its natural ligand angiopoietin-1 Scientific Reports, 2021-07-07;11(1):14021. 2021-07-07 [PMID: 34234265] (Bioassay, Human)	Bioassay	Human
S Fujiwara-S, Y Ueda, M Fujikawa, M Osaki, N Yamanaka, T Matsumoto Mucopolysaccharide polysulfate promotes microvascular stabilization and barrier integrity of dermal microvascular endothelial cells via activation of the angiopoietin-1/Tie2 pathway Journal of dermatological science, 2021-06-02;0(0):. 2021-06-02 [PMID: 34148739] (Bioassay, Human)	Bioassay	Human
I Paredes, JR Vieira, B Shah, CF Ramunno, J Dyckow, H Adler, M Richter, G Schermann, E Giannakour, L Schirmer, HG Augustin, C Ruiz de Al Oligodendrocyte precursor cell specification is regulated by bidirectional neural progenitor-endothelial cell crosstalk Nature Neuroscience, 2021-01-28;0(0):. 2021-01-28 [PMID: 33510480] (Bioassay, Mouse)	Bioassay	Mouse
S Harel, V Sanchez-Go, R Echavarria, D Mayaki, SN Hussain Roles of miR-640 and Zinc Finger Protein 91 (ZFP91) in Angiopoietin-1-Induced In Vitro Angiogenesis Cells, 2020-07-02;9(7):. 2020-07-02 [PMID: 32630670] (Cell Culture, Human)	Cell Culture	Human
S Gadomski, SK Singh, S Singh, T Sarkar, KD Klarmann, M Berenschot, S Seaman, B Jakubison, KO Gudmundsso, S Lockett, JR Keller Id1 and Id3 Maintain Steady-State Hematopoiesis by Promoting Sinusoidal Endothelial Cell Survival and Regeneration Cell Rep, 2020-04-28;31(4):107572. 2020-04-28 [PMID: 32348770] (Bioassay, Mouse)	Bioassay	Mouse
M Singhal, N Gengenbach, S La Porta, S Gehrs, J Shi, M Kamiyama, DM Bodenmille, A Fischl, B Schieb, E Besemfelde, S Chintharla, HG Augustin Preclinical validation of a novel metastasis-inhibiting Tie1 function-blocking antibody EMBO Mol Med, 2020-04-17;0(0):e11164. 2020-04-17 [PMID: 32302470] (Bioassay, Human)	Bioassay	Human
EA Thackaberr, Y Zhou, CL Zuch de Za, G Fuh, CV Lee, S Sanowar, JB Ridgway, AM Kusi, C Farman, H Booler, D Sheinson, CA Rasmussen, PE Miller, E Wakshull, M Yan, V Bantseev Rapid Development of Glaucoma Via ITV Nonselective ANGPT 1/2 Antibody: A Potential Role for ANGPT/TIE2 Signaling in Primate Aqueous Humor Outflow Invest. Ophthalmol. Vis. Sci., 2019-10-01;60(13):4097-4108. 2019-10-01 [PMID: 31574535] (Bioassay, Human)	Bioassay	Human
T Muraguchi, D Nanba, EK Nishimura, T Tashiro IGF-1R deficiency in human keratinocytes disrupts epidermal homeostasis and stem cell maintenance J. Dermatol. Sci., 2019-05-11;0(0):. 2019-05-11 [PMID: 31122679] (Bioassay, Human)	Bioassay	Human
S Stephenson, MA Care, I Fan, A Zougman, DR Westhead, GM Doody, RM Tooze Growth Factor-like Gene Regulation Is Separable from Survival and Maturation in Antibody-Secreting Cells J. Immunol., 2019-01-14;202(4):1287-1300. 2019-01-14 [PMID: 30642980] (Bioassay, Human)	Bioassay	Human
H Elamaa, M Kihlström, E Kapiainen, M Kaakinen, I Miinalaine, S Ragauskas, M Cerrada-Gi, S Mering, M Nätynki, L Eklund Angiopoietin-4-dependent venous maturation and fluid drainage in the peripheral retina Elife, 2018-11-16;7(0):. 2018-11-16 [PMID: 30444491] (Bioassay, ELISA (Capture), Surface Plasmon Resonance, Human)	Bioassay, ELISA (Capture), Surface Plasmon Resonance	Human
SJ Higgins, K Ceunynck, J Kellum, X Chen, X Gu, SA Chaudhry, S Schulman, TA Libermann, S Lu, NI Shapiro, DC Christiani, R Flaumenhaf, SM Parikh Tie2 protects the vasculature against thrombus formation in systemic inflammation J. Clin. Invest., 2018-03-05;0(0):. 2018-03-05 [PMID: 29360642] (Bioassay, Human)	Bioassay	Human
T Souma, BR Thomson, S Heinen, IA Carota, S Yamaguchi, T Onay, P Liu, AK Ghosh, C Li, V Eremina, YK Hong, AN Economides, D Vestweber, KG Peters, J Jin, SE Quaggin Context-dependent functions of angiopoietin 2 are determined by the endothelial phosphatase VEPTP Proc. Natl. Acad. Sci. U.S.A., 2018-01-22;0(0):. 2018-01-22 [PMID: 29358379] (Bioassay, Human)	Bioassay	Human
S La Porta, L Roth, M Singhal, C Mogler, C Spegg, B Schieb, X Qu, RH Adams, HS Baldwin, S Savant, HG Augustin Endothelial Tie1-mediated angiogenesis and vascular abnormalization promote tumor progression and metastasis J. Clin. Invest., 2018-01-22;0(0):. 2018-01-22 [PMID: 29355844] (Bioassay, Human)	Bioassay	Human
C Daly, X Qian, C Castanaro, E Pasnikowsk, X Jiang, BR Thomson, SE Quaggin, N Papadopoul, Y Wei, JS Rudge, G Thurston, GD Yancopoulo, S Davis Angiopoietins bind thrombomodulin and inhibit its function as a thrombin cofactor Sci Rep, 2018-01-11;8(1):505. 2018-01-11 [PMID: 29323190] (Bioassay, Human)	Bioassay	Human
LY Pan, YF Chen, HC Li, LM Bi, WJ Sun, GF Sun, XF Zhang, K Xu, DX Feng Dachengqi Decoction Attenuates Intestinal Vascular Endothelial Injury in Severe Acute Pancreatitis in Vitro and in Vivo Cell. Physiol. Biochem., 2017-12-18;44(6):2395-2406. 2017-12-18 [PMID: 29262394] (Bioassay, Human)	Bioassay	Human
G Eich, M Bartosova, C Tischer, TT Wlodkowski, B Schaefer, S Pichl, N Kraewer, B Ranchin, K Vondrak, MC Liebau, T Hackert, CP Schmitt Bicarbonate buffered peritoneal dialysis fluid upregulates angiopoietin-1 and promotes vessel maturation PLoS ONE, 2017-12-18;12(12):e0189903. 2017-12-18 [PMID: 29253861] (Bioassay, Human)	Bioassay	Human
B Gutbier, X Jiang, K Dietert, C Ehrler, J Lienau, P Van Slyke, H Kim, VC Hoang, JT Maynes, DJ Dumont, AD Gruber, N Weissmann, TJ Mitchell, N Suttorp, M Witzenrath Vasculotide reduces pulmonary hyperpermeability in experimental pneumococcal pneumonia Crit Care, 2017-11-13;21(1):274. 2017-11-13 [PMID: 29132435] (Bioassay, Mouse)	Bioassay	Mouse
J Chen, Y Luo, H Hui, T Cai, H Huang, F Yang, J Feng, J Zhang, X Yan CD146 coordinates brain endothelial cell-pericyte communication for blood-brain barrier development Proc. Natl. Acad. Sci. U.S.A., 2017-08-21;0(0):. 2017-08-21 [PMID: 28827364] (Bioassay, Mouse)	Bioassay	Mouse
A Burnett, I Gomez, DD De Leon, M Ariaans, P Progias, RA Kammerer, G Velasco, M Marron, P Hellewell, V Ridger Angiopoietin-1 enhances neutrophil chemotaxis in vitro and migration in vivo through interaction with CD18 and release of CCL4 Sci Rep, 2017-05-24;7(1):2332. 2017-05-24 [PMID: 28539655] (Bioassay, Mouse)	Bioassay	Mouse
T Shlamkovic, L Aharon, WA Barton, N Papo Utilizing combinatorial engineering to develop Tie2 targeting antagonistic angiopoetin-2 ligands as candidates for anti-angiogenesis therapy Oncotarget, 2017-05-16;8(20):33571-33585. 2017-05-16 [PMID: 28422724] (Control, Human)	Control	Human
JO Moore, MA Lemmon, KM Ferguson Dimerization of Tie2 mediated by its membrane-proximal FNIII domains Proc. Natl. Acad. Sci. U.S.A., 2017-04-10;0(0):. 2017-04-10 [PMID: 28396397] (Bioassay, Human)	Bioassay	Human
K Wang, W Liu, Y Song, X Wu, Y Zhang, S Li, Y Gao, J Tu, Y Liu, C Yang The role of angiopoietin-2 in nucleus pulposus cells during human intervertebral disc degeneration Lab. Invest., 2017-04-10;0(0):. 2017-04-10 [PMID: 28394321] (Bioassay, Human)	Bioassay	Human
YT Ho, G Adriani, S Beyer, PT Nhan, RD Kamm, JC Kah A Facile Method to Probe the Vascular Permeability of Nanoparticles in Nanomedicine Applications Sci Rep, 2017-03-31;7(1):707. 2017-03-31 [PMID: 28386096] (Bioassay, Human)	Bioassay	Human
N Morooka, S Futaki, R Sato-Nishi, M Nishino, Y Totani, C Shimono, I Nakano, H Nakajima, N Mochizuki, K Sekiguchi Polydom Is an Extracellular Matrix Protein Involved in Lymphatic Vessel Remodeling Circ. Res, 2017-02-08;0(0):. 2017-02-08 [PMID: 28179430] (Bioassay, Mouse)	Bioassay	Mouse
L J Spicer G protein-coupled receptor 34 in ovarian granulosa cells of cattle: changes during follicular development and potential functional implications Domest. Anim. Endocrinol, 2016-12-11;59(0):90-99. 2016-12-11 [PMID: 28040605] (Bioassay, Bovine)	Bioassay	Bovine
TIE2-mediated tyrosine phosphorylation of H4 regulates DNA damage response by recruiting ABL1 Sci Adv, 2016-04-01;2(4):e1501290. 2016-04-01 [PMID: 27757426] (Bioassay, Human)	Bioassay	Human
Angiogenic microspheres promote neural regeneration and motor function recovery after spinal cord injury in rats Sci Rep, 2016-09-19;6(0):33428. 2016-09-19 [PMID: 27641997] (In Vivo, Rat)	In Vivo	Rat
New Insights into the Pro-Inflammatory Activities of Ang1 on Neutrophils: Induction of MIP-1? Synthesis and Release PLoS ONE, 2016-09-15;11(9):e0163140. 2016-09-15 [PMID: 27632174] (Bioassay, Human)	Bioassay	Human
Tie1 controls angiopoietin function in vascular remodeling and inflammation J Clin Invest, 2016-08-22;0(0):. 2016-08-22 [PMID: 27548530] (Bioassay, Human)	Bioassay	Human
Wilson Chan Fibulin-5 Regulates Angiopoietin-1/Tie-2 Receptor Signaling in Endothelial Cells PLoS ONE, 2016-06-15;11(6):e0156994. 2016-06-15 [PMID: 27304216] (Bioassay, Human)	Bioassay	Human
Phanthanawiboon S, Limkittikul K, Sakai Y, Takakura N, Saijo M, Kurosu T Acute Systemic Infection with Dengue Virus Leads to Vascular Leakage and Death through Tumor Necrosis Factor-alpha and Tie2/Angiopoietin Signaling in Mice Lacking Type I and II Interferon Receptors. PLoS ONE, 2016-02-04;11(2):e0148564. 2016-02-04 [PMID: 26844767] (In Vivo, Mouse)	In Vivo	Mouse
Siddiqui M, Mayanil C, Kim K, Tomita T Angiopoietin-1 Regulates Brain Endothelial Permeability through PTPN-2 Mediated Tyrosine Dephosphorylation of Occludin. PLoS ONE, 2015-06-19;10(6):e0130857. 2015-06-19 [PMID: 26090670] (Bioassay, Human)	Bioassay	Human
Hakanpaa L, Sipila T, Leppanen V, Gautam P, Nurmi H, Jacquemet G, Eklund L, Ivaska J, Alitalo K, Saharinen P Endothelial destabilization by angiopoietin-2 via integrin beta1 activation. Nat Commun, 2015-01-30;6(0):5962. 2015-01-30 [PMID: 25635707] (Bioassay, Human)	Bioassay	Human
Wang S, Amato K, Song W, Youngblood V, Lee K, Boothby M, Brantley-Sieders D, Chen J Regulation of endothelial cell proliferation and vascular assembly through distinct mTORC2 signaling pathways. Mol Cell Biol, 2015-01-12;35(7):1299-313. 2015-01-12 [PMID: 25582201] (Bioassay, Mouse)	Bioassay	Mouse
Korpela , Elina, Yohan , Darren, Chin , Lee Cl, Kim , Anthony, Huang , Xiaoyong, Sade , Shachar, Van Slyke , Paul, Dumont , Daniel J, Liu , Stanley Vasculotide, an Angiopoietin-1 mimetic, reduces acute skin ionizing radiation damage in a preclinical mouse model. BMC Cancer, 2014-08-26;14(0):614. 2014-08-26 [PMID: 25159192] (Bioassay, Human)	Bioassay	Human
Brunckhorst M, Xu Y, Lu R, Yu Q Angiopoietins promote ovarian cancer progression by establishing a procancer microenvironment. Am J Pathol, 2014-08-01;184(8):2285-96. 2014-08-01 [PMID: 25043619] (Bioassay, Human)	Bioassay	Human
Tahir T, Singh H, Brindle N The RNA binding protein hnRNP-K mediates post-transcriptional regulation of uncoupling protein-2 by angiopoietin-1. Cell Signal, 2014-03-15;26(7):1379-84. 2014-03-15 [PMID: 24642125] (Bioassay, Human)	Bioassay	Human
Yao J, Cui M, Li M, Liu Y, He Q, Xiao J, Bai Y Angiopoietin1 inhibits mast cell activation and protects against anaphylaxis. PLoS ONE, 2014-02-19;9(2):e89148. 2014-02-19 [PMID: 24586553] (Bioassay, Mouse)	Bioassay	Mouse
Haddad L, Sirois M Angiopoietin-1 upregulates de novo expression of IL-1beta and Il1-Ra, and the exclusive release of Il1-Ra from human neutrophils. PLoS ONE, 2014-02-12;9(2):e88980. 2014-02-12 [PMID: 24563688] (Bioassay, Human)	Bioassay	Human
Grafton K, Moir L, Black J, Hansbro N, Hansbro P, Burgess J, Oliver B LF-15 & T7, synthetic peptides derived from tumstatin, attenuate aspects of airway remodelling in a murine model of chronic OVA-induced allergic airway disease. PLoS ONE, 2014-01-15;9(1):e85655. 2014-01-15 [PMID: 24454912] (Bioassay, Human)	Bioassay	Human
Pellegrinelli V, Rouault C, Veyrie N, Clement K, Lacasa D Endothelial cells from visceral adipose tissue disrupt adipocyte functions in a three-dimensional setting: partial rescue by angiopoietin-1. Diabetes, 2013-10-15;63(2):535-49. 2013-10-15 [PMID: 24130331] (Bioassay, Human)	Bioassay	Human
Brindle , Nicholas, Sale , Julian E, Arakawa , Hiroshi, Buerstedde , Jean-Mar, Nuamchit , Teonchit, Sharma , Shikha, Steele , Kathryn Directed evolution of an angiopoietin-2 ligand trap by somatic hypermutation and cell surface display. J Biol Chem, 2013-10-08;288(46):33205-12. 2013-10-08 [PMID: 24106271] (Bioassay, Human)	Bioassay	Human
Jin H, Bae Y, Kim M, Kwon S, Jeon H, Choi S, Kim S, Yang Y, Oh W, Chang J Comparative analysis of human mesenchymal stem cells from bone marrow, adipose tissue, and umbilical cord blood as sources of cell therapy. Int J Mol Sci, 2013-09-03;14(9):17986-8001. 2013-09-03 [PMID: 24005862] (Bioassay, Rat)	Bioassay	Rat
Yu , Xuehong, Seegar , Tom C M, Dalton , Annamari, Tzvetkova-Robev , Dorothea, Goldgur , Yehuda, Rajashankar , Kanagala, Nikolov , Dimitar, Barton , William Structural basis for angiopoietin-1-mediated signaling initiation. Proc Natl Acad Sci U S A, 2013-04-16;110(18):7205-10. 2013-04-16 [PMID: 23592718] (Bioassay, Human)	Bioassay	Human
Yamakawa , Daishi, Kidoya , Hiroyasu, Sakimoto , Susumu, Jia , Weizhen, Naito , Hisamich, Takakura , Nobuyuki Ligand-independent Tie2 dimers mediate kinase activity stimulated by high dose angiopoietin-1. J Biol Chem, 2013-03-15;288(18):12469-77. 2013-03-15 [PMID: 23504320] (Bioassay, Human, Mouse)	Bioassay	Human, Mouse
Hanjaya-Putra D, Shen Y, Wilson A, Fox-Talbot K, Khetan S, Burdick J, Steenbergen C, Gerecht S Integration and regression of implanted engineered human vascular networks during deep wound healing. Stem Cells Transl Med, 2013-03-13;2(4):297-306. 2013-03-13 [PMID: 23486832] (Bioassay, Human)	Bioassay	Human
David S, Park JK, Meurs M, Zijlstra JG, Koenecke C, Schrimpf C, Shushakova N, Gueler F, Haller H, Kumpers P Acute administration of recombinant Angiopoietin-1 ameliorates multiple-organ dysfunction syndrome and improves survival in murine sepsis. Cytokine, 2011-04-30;55(2):251-9. 2011-04-30 [PMID: 21531574] (In Vivo, Mouse)	In Vivo	Mouse
Brunckhorst MK, Wang H, Lu R, Yu Q Angiopoietin-4 promotes glioblastoma progression by enhancing tumor cell viability and angiogenesis. Cancer Res., 2010-09-07;70(18):7283-93. 2010-09-07 [PMID: 20823154] (Bioassay, Human)	Bioassay	Human
Song H, Suehiro J, Kanki Y, Kawai Y, Inoue K, Daida H, Yano K, Ohhashi T, Oettgen P, Aird WC, Kodama T, Minami T Critical role for GATA3 in mediating Tie2 expression and function in large vessel endothelial cells. J. Biol. Chem., 2009-08-12;284(42):29109-24. 2009-08-12 [PMID: 19674970] (Bioassay, Human)	Bioassay	Human
Dallabrida SM, Ismail NS, Pravda EA, Parodi EM, Dickie R, Durand EM, Lai J, Cassiola F, Rogers RA, Rupnick MA Integrin binding angiopoietin-1 monomers reduce cardiac hypertrophy. FASEB J., 2008-05-23;22(8):3010-23. 2008-05-23 [PMID: 18502941] (Western Blot)	Western Blot
Saharinen P, Eklund L, Miettinen J, Wirkkala R, Anisimov A, Winderlich M, Nottebaum A, Vestweber D, Deutsch U, Koh GY, Olsen BR, Alitalo K Angiopoietins assemble distinct Tie2 signalling complexes in endothelial cell-cell and cell-matrix contacts. Nat. Cell Biol., 2008-04-20;10(5):527-37. 2008-04-20 [PMID: 18425119] (Bioassay, Human)	Bioassay	Human
Rao S, Lobov IB, Vallance JE, Tsujikawa K, Shiojima I, Akunuru S, Walsh K, Benjamin LE, Lang RA Obligatory participation of macrophages in an angiopoietin 2-mediated cell death switch. Development, 2007-12-01;134(24):4449-58. 2007-12-01 [PMID: 18039971] (In Vivo, Mouse)	In Vivo	Mouse
Clavel G, Bessis N, Lemeiter D, Fardellone P, Mejjad O, Menard JF, Pouplin S, Boumier P, Vittecoq O, Le Loet X, Boissier MC Angiogenesis markers (VEGF, soluble receptor of VEGF and angiopoietin-1) in very early arthritis and their association with inflammation and joint destruction. Clin. Immunol., 2007-06-08;124(2):158-64. 2007-06-08 [PMID: 17560831] (ELISA (Standard))	ELISA (Standard)
Riccioni R, Diverio D, Mariani G, Buffolino S, Riti V, Saulle E, Petrucci E, Cedrone M, Lo-Coco F, Foa R, Peschle C, Testa U Expression of Tie-2 and other receptors for endothelial growth factors in acute myeloid leukemias is associated with monocytic features of leukemic blasts. Stem Cells, 2007-04-19;25(8):1862-71. 2007-04-19 [PMID: 17446561] (Bioassay, Human)	Bioassay	Human
Ohab JJ, Fleming S, Blesch A, Carmichael ST A neurovascular niche for neurogenesis after stroke. J. Neurosci., 2006-12-13;26(50):13007-16. 2006-12-13 [PMID: 17167090] (In Vivo, Mouse)	In Vivo	Mouse
Kalomenidis I, Kollintza A, Sigala I, Papapetropoulos A, Papiris S, Light RW, Roussos C Angiopoietin-2 levels are elevated in exudative pleural effusions. Chest, 2006-05-01;129(5):1259-66. 2006-05-01 [PMID: 16685017] (ELISA (Standard))	ELISA (Standard)
Horst AK, Ito WD, Dabelstein J, Schumacher U, Sander H, Turbide C, Brummer J, Meinertz T, Beauchemin N, Wagener C Carcinoembryonic antigen-related cell adhesion molecule 1 modulates vascular remodeling in vitro and in vivo. J. Clin. Invest., 2006-05-04;116(6):1596-605. 2006-05-04 [PMID: 16680193] (In Vivo, Mouse)	In Vivo	Mouse
Tsigkos S, Zhou Z, Kotanidou A, Fulton D, Zakynthinos S, Roussos C, Papapetropoulos A Regulation of Ang2 release by PTEN/PI3-kinase/Akt in lung microvascular endothelial cells. J. Cell. Physiol., 2006-05-01;207(2):506-11. 2006-05-01 [PMID: 16447257] (Bioassay, Bovine)	Bioassay	Bovine
Satchell SC, Anderson KL, Mathieson PW Angiopoietin 1 and vascular endothelial growth factor modulate human glomerular endothelial cell barrier properties. J. Am. Soc. Nephrol., 2004-03-01;15(3):566-74. 2004-03-01 [PMID: 14978158] (Bioassay, Human)	Bioassay	Human
Caine GJ, Blann AD, Stonelake PS, Ryan P, Lip GY Plasma angiopoietin-1, angiopoietin-2 and Tie-2 in breast and prostate cancer: a comparison with VEGF and Flt-1. Eur. J. Clin. Invest., 2003-10-01;33(10):883-90. 2003-10-01 [PMID: 14511360] (ELISA (Standard))	ELISA (Standard)
Danet GH, Pan Y, Luongo JL, Bonnet DA, Simon MC Expansion of human SCID-repopulating cells under hypoxic conditions. J. Clin. Invest., 2003-07-01;112(1):126-35. 2003-07-01 [PMID: 12840067] (Bioassay, Human)	Bioassay	Human
Show All 68 Publications. Collapse Publications.

Array 923-AN/CF

• Angiopoietin-1 Antibodies
• Angiopoietin-1 ELISA Kits
• Angiopoietin-1 Lysate
• Angiopoietin-1 Proteins
• Angiopoietin-1 ELISAs
• Angiopoietin-1 Proteins and Enzymes