RanBP1 Antibody Summary
Immunogen |
The immunogen recognized by this antibody maps to a region between residue 150 and the C-terminus (residue 201) of human RAN Binding Protein 1 using the numbering given in entry NP_002873.1 (GeneID 5902). |
Isotype |
IgG |
Clonality |
Polyclonal |
Host |
Rabbit |
Gene |
RANBP1 |
Purity |
Immunogen affinity purified |
Innovator's Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase. |
Applications/Dilutions
Dilutions |
- Immunohistochemistry
- Immunoprecipitation 2-5 ug/mg lysate
- Western Blot
|
Control |
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Packaging, Storage & Formulations
Storage |
Store at 4C. Do not freeze. |
Buffer |
Tris-Citrate/Phosphate (pH 7.0 - 8.0) |
Preservative |
0.09% Sodium Azide |
Concentration |
1.0 mg/ml |
Purity |
Immunogen affinity purified |
Alternate Names for RanBP1 Antibody
Background
Ran/TC4-binding protein, RanBP1, interacts specifically with GTP-charged RAN. RANBP1 encodes a 23-kD protein that binds to RAN complexed with GTP but not GDP. RANBP1 does not activate GTPase activity of RAN but does markedly increase GTP hydrolysis by the RanGTPase-activating protein (RanGAP1). The RANBP1 cDNA encodes a 201-amino acid protein that is 92% similar to its mouse homolog. In both mammalian cells and in yeast, RANBP1 acts as a negative regulator of RCC1 by inhibiting RCC1-stimulated guanine nucleotide release from RAN.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are
guaranteed for 1 year from date of receipt.
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Product General Protocols
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FAQs for RanBP1 Antibody (NB100-79815) (0)
Control Lysate(s)
Secondary Antibodies
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Isotype Controls
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