PTP gamma/PTPRG Antibody (481505)

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Protein Tyrosine Phosphatase, Receptor type gamma (PTPR gamma ), also called PTPRG and PTPG, is a transmembrane protein. Its extracellular region contains carbonic anhydrase fibronectin III domains, suggesting that it interacts with adhesion molecules, but the only reported activator is an intracellular ATP-dependent factor. During brain development, PTPR gamma is found exclusively in post-mitotic neurons. A wide variety of cancers, including colon, renal clear cell, lung, breast, and cervical cancers, show a high incidence of defects in the PTPR gamma gene, suggesting the protein has a key regulatory function in tumor suppression.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 2 confirmed species: Human, Mouse.

We have publications tested in 1 application: Western Blot.

Showing Publications 1 - 2 of 2.

Publications using MAB4608	Applications	Species
Moratti E, Vezzalini M, Tomasello L, Giavarina D, Sorio C Identification of protein tyrosine phosphatase receptor gamma extracellular domain (sPTPRG) as a natural soluble protein in plasma. PLoS ONE, 2015-03-16;10(3):e0119110. 2015-03-16 [PMID: 25775014] (Western Blot, Human, Mouse)	Western Blot	Human, Mouse
Mirenda M, Toffali L, Montresor A, Scardoni G, Sorio C, Laudanna C Protein tyrosine phosphatase receptor type gamma is a JAK phosphatase and negatively regulates leukocyte integrin activation. J Immunol, 2015-01-26;194(5):2168-79. 2015-01-26 [PMID: 25624455] (Western Blot, Human)	Western Blot	Human

Array MAB4608

• PTP gamma/PTPRG Antibodies
• PTP gamma/PTPRG ELISA Kits
• PTP gamma/PTPRG Protein