PTP gamma/PTPRG Products

Description

PTPRG is encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. The extracellular region of this PTP contains a carbonic anhydrase-like (CAH) domain, which is also found in the extracellular region of PTPRBETA/ZETA. This gene is located in a chromosomal region that is frequently deleted in renal cell carcinoma and lung carcinoma, thus is thought to be a candidate tumor suppressor gene. [provided by RefSeq]

Bioinformatics

Entrez	5793 Human
Uniprot	AAH47734.1 Human P23470 Human
Product By Gene ID	5793
Alternate Names	EC 3.1.3.48 H_RG317H01.1 HPTPG protein tyrosine phosphatase, receptor type, G protein tyrosine phosphatase, receptor type, gamma polypeptide Protein-tyrosine phosphatase gamma PTPGprotein tyrosine phosphatase gamma receptor type protein tyrosine phosphatase gamma receptor tyrosine phosphatase gamma receptor-type protein phosphatase gamma receptor-type tyrosine-protein phosphatase gamma RPTPG R-PTP-GAMMA R-PTP-gamma