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Protein Disulfide Isomerase/P4HB Antibody (16) [Janelia Fluor® 669]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ELISA, ICC/IF, IP
Clone
16
Clonality
Monoclonal
Host
Rabbit
Conjugate
Janelia Fluor 669

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NBP2-89676AF350
Alexa Fluor 405
NBP2-89676AF405
Alexa Fluor 488
NBP2-89676AF488
Alexa Fluor 532
NBP2-89676AF532
Alexa Fluor 594
NBP2-89676AF594
Alexa Fluor 647
NBP2-89676AF647
Alexa Fluor 700
NBP2-89676AF700
Alexa Fluor 750
NBP2-89676AF750
Allophycocyanin
NBP2-89676APC
Biotin
NBP2-89676B
CoraFluor 1
NBP2-89676CL1
DyLight 350
NBP2-89676UV
DyLight 405
NBP2-89676V
DyLight 488
NBP2-89676G
DyLight 550
NBP2-89676R
DyLight 594
NBP2-89676DL594
DyLight 650
NBP2-89676C
DyLight 680
NBP2-89676FR
DyLight 755
NBP2-89676IR
FITC
NBP2-89676F
HRP
NBP2-89676H
Janelia Fluor 525
NBP2-89676JF525
Janelia Fluor 549
NBP2-89676JF549
Janelia Fluor 646
NBP2-89676JF646
PE
NBP2-89676PE
PerCP
NBP2-89676PCP
Unconjugated
NBP2-89676-100ul
mFluor Violet 450 SE
NBP2-89676MFV450
mFluor Violet 500 SE
NBP2-89676MFV500
mFluor Violet 610 SE
NBP2-89676MFV610
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Protein Disulfide Isomerase/P4HB Antibody (16) [Janelia Fluor® 669] Summary

Additional Information
Recombinant Monoclonal Antibody
Immunogen
This antibody was obtained from a rabbit immunized with purified, recombinant Human Protein Disulfide Isomerase/P4HB (Accession#: NP_000909.2; Met 1-Lys 505).
Isotype
IgG
Clonality
Monoclonal
Host
Rabbit
Gene
P4HB
Purity
Protein A purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
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Applications/Dilutions

Dilutions
  • ELISA
  • Immunocytochemistry/ Immunofluorescence
  • Immunoprecipitation
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A purified

Notes



Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for Protein Disulfide Isomerase/P4HB Antibody (16) [Janelia Fluor® 669]

  • Cellular thyroid hormone-binding protein
  • collagen prolyl 4-hydroxylase beta
  • DSI
  • ERBA2L
  • GIT
  • glutathione-insulin transhydrogenase
  • P4HB
  • P4Hbeta
  • p55
  • PDI
  • PDIA1
  • PDIA1procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), betapolypeptide (protein disulfide isomerase-associated 1)
  • PDIEC 5.3.4.1
  • PHDB
  • PO4DB
  • PO4HB
  • procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), betapolypeptide
  • PROHB
  • PROHBprocollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), betapolypeptide (protein disulfide isomerase; thyroid hormone binding protein p55)
  • Prolyl 4-hydroxylase subunit beta
  • prolyl 4-hydroxylase, beta polypeptide
  • protein disulfide isomerase family A, member 1
  • protein disulfide isomerase/oxidoreductase
  • protein disulfide isomerase-associated 1
  • protein disulfide-isomerase
  • protocollagen hydroxylase
  • Thbp
  • thyroid hormone-binding protein p55

Background

P4HB, the beta subunit of prolyl 4-hydroxylase, a highly abundant member of the PDI family. P4HB is a multifunctional enzyme, involved in hydroxylation of prolyl residues in preprocollagen, as well as continual rearrangement of disulfide bonds. Other known functions include its ability to act as a chaperone that inhibits aggregation of misfolded proteins in a concentration-dependent manner, its ability to bind thyroid hormone, its role in both the influx and efflux of S-nitrosothiol-bound nitric oxide, and its function as a subunit of the microsomal triglyceride transfer protein complex.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol P4HB