PITRM1 Antibody - BSA Free

Images

 
Western Blot: PITRM1 Antibody [NBP2-19844] - Sample (30 ug of whole cell lysate) A: PC-3 B: U87-MG 7. 5% SDS PAGE gel, diluted at 1:1000.
Immunocytochemistry/ Immunofluorescence: PITRM1 Antibody [NBP2-19844] - SKNSH cells were fixed in ice-cold MeOH for 5 min. Green: PITRM1 protein stained by PITRM1 antibody diluted at 1:500. Blue: Hoechst 33342 ...read more
Immunohistochemistry-Paraffin: PITRM1 Antibody [NBP2-19844] - Analysis of paraffin-embedded Gastric ca, using antibody at 1:500 dilution.

Product Details

Summary
Reactivity Hu, PmSpecies Glossary
Applications WB, ICC/IF, IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Format
BSA Free

Order Details

PITRM1 Antibody - BSA Free Summary

Immunogen
Recombinant protein encompassing a sequence within the center region of human PITRM1. The exact sequence is proprietary.
Localization
Mitochondrion matrix
Predicted Species
Chimpanzee (99%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
PITRM1
Purity
Antigen Affinity-purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunocytochemistry/ Immunofluorescence 1:100-1:1000
  • Immunohistochemistry 1:100-1:1000
  • Immunohistochemistry-Paraffin 1:100-1:1000
  • Western Blot 1:500-1:3000
Theoretical MW
117 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Reactivity Notes

Mouse (85%), Rat (85%).

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
0.1M Tris (pH 7), 0.1M Glycine, 20% Glycerol
Preservative
0.01% Thimerosal
Purity
Antigen Affinity-purified

Alternate Names for PITRM1 Antibody - BSA Free

  • EC 3.4.24
  • EC 3.4.24.-
  • hPreP
  • Metalloprotease 1
  • MGC138192
  • MGC141929
  • pitrilysin metallopeptidase 1
  • Pitrilysin metalloproteinase 1mitochondrial
  • PreP

Background

ATP-independent protease that degrades mitochondrial transit peptides after their cleavage. Also degrades other unstructured peptides. Specific for peptides in the range of 10 to 65 residues. Able to degrade amyloid beta A4 (APP) protein when it accumulates in mitochondrion, suggesting a link with Alzheimer disease. Shows a preference for cleavage after small polar residues and before basic residues, but without any positional preference

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

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Bioinformatics

Gene Symbol PITRM1