PHLDA3 Antibody

Images

 
Immunohistochemistry-Paraffin: PHLDA3 Antibody [NBP1-80683] -Staining of human colon shows moderate cytoplasmic positivity in glandular cells.
Immunohistochemistry-Paraffin: PHLDA3 Antibody [NBP1-80683] -Staining of human skeletal muscle shows moderate cytoplasmic positivity in myocytes.
Immunohistochemistry-Paraffin: PHLDA3 Antibody [NBP1-80683] -Staining of human urinary bladder shows moderate cytoplasmic positivity in urothelial cells.
Immunohistochemistry-Paraffin: PHLDA3 Antibody [NBP1-80683] -Staining of human tonsil shows very weak positivity in germinal center cells as expected.

Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

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PHLDA3 Antibody Summary

Immunogen
This antibody was developed against Recombinant Protein corresponding to amino acids: LWKRKRCVLTERGLQLFEAKGTGGRPKELSFARIKAVECVESTGRHIYFTLVTEGGGEIDFRCPLEDPGWNAQITLGLVKFKNQQAIQTVR
Predicted Species
Mouse (100%), Rat (99%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
PHLDA3
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:50 - 1:200
  • Immunohistochemistry-Paraffin 1:50 - 1:200
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Control Peptide
PHLDA3 Protein (NBP1-80683PEP)
Publications
Read Publications using
NBP1-80683 in the following applications:

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for PHLDA3 Antibody

  • family A, member 2
  • pleckstrin homology-like domain, family A, member 3
  • TIH1TDAG51/Ipl homolog 1

Background

p53/TP53-regulated repressor of Akt/AKT1 signaling. Represses AKT1 by preventing AKT1-binding to membrane lipids, thereby inhibiting AKT1 translocation to the cellular membrane and activation. Contributes to p53/TP53-dependent apoptosis by repressing AKT1 activity. Its directs transcription regulation by p53/TP53 may explain how p53/TP53 can negatively regulate AKT1. May acts as a tumor suppressor

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for PHLDA3 Antibody (NBP1-80683)(2)

We have publications tested in 1 confirmed species: Human.

We have publications tested in 3 applications: FLOW, IF/IHC, WB.


Filter By Application
FLOW
(1)
IF/IHC
(1)
WB
(1)
All Applications
Filter By Species
Human
(2)
All Species

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol PHLDA3
Entrez
Uniprot