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PER1 Antibody [Unconjugated]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications IHC
Clonality
Polyclonal
Host
Goat
Conjugate
Unconjugated
Concentration
LYOPH

Order Details

View Available Formulations
Catalog# & Formulation Size Price
Carrier Free
AF4565-SP
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PER1 Antibody [Unconjugated] Summary

Immunogen
E. coli-derived recombinant human PER1
Ser159-Thr365
Accession # O15534
Specificity
Detects human PER1 in direct ELISAs.
Source
N/A
Isotype
IgG
Clonality
Polyclonal
Host
Goat
Gene
PER1
Purity Statement
Antigen Affinity-purified
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Applications/Dilutions

Dilutions
  • Immunohistochemistry 5-15 ug/mL

Packaging, Storage & Formulations

Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Preservative
No Preservative
Concentration
LYOPH
Reconstitution Instructions
Reconstitute at 0.2 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for PER1 Antibody [Unconjugated]

  • Circadian clock protein PERIOD 1
  • Circadian pacemaker protein Rigui
  • hPER1
  • KIAA0482
  • PER1
  • PERhPER
  • period (Drosophila) homolog 1
  • period circadian protein homolog 1
  • period homolog 1 (Drosophila)
  • Period, drosophila, homolog of
  • PERIOD1
  • RIGUI
  • RIGUIMGC88021

Background

PER1 (Period circadian protein 1; also known as RIGUI) is a 188 kDa member of the PER family of molecules. It apparently influences circadian rhythms by interacting with, and stabilizing, other circadian regulatory proteins. PER1 undergoes extensive phosphorylation that may regulate its intracellular localization. Human PER1 is 1290 amino acids (aa) in length. It contains a bHLH region (aa 122-173), an extended PAS domain (aa 183-463) plus an NLS and NES. Multiple splice forms exist. Two show deletions (aa 741-820 and aa 209-217), while two show aa substitutions: 9 aa for the C-terminal 1005 aa, and 29 aa for the C-terminal 747 amino acids. Over aa 159-365, human PER1 is 96% identical to mouse, rat, and dog PER1.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol PER1
Uniprot