PBEF/Visfatin/NAMPT Antibody (362616) [Unconjugated] Summary
Immunogen |
Mouse myeloma cell line NS0-derived recombinant mouse PBEF/Visfatin Met1-His491 Accession # Q99KQ4 |
Specificity |
Detects human and mouse PBEF/Visfatin in direct ELISAs and Western blots. In direct ELISAs and Western blots, 100% cross-reactivity with recombinant human PBEF is observed. |
Source |
N/A |
Isotype |
IgG2a |
Clonality |
Monoclonal |
Host |
Rat |
Gene |
NAMPT |
Purity Statement |
Protein A or G purified from hybridoma culture supernatant |
Innovator's Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase. |
Applications/Dilutions
Dilutions |
- CyTOF-ready
- Intracellular Staining by Flow Cytometry 2.5 ug/10^6 cells
- Western Blot 1 ug/mL
|
Publications |
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Packaging, Storage & Formulations
Storage |
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. - 12 months from date of receipt, -20 to -70 °C as supplied.
- 1 month, 2 to 8 °C under sterile conditions after reconstitution.
- 6 months, -20 to -70 °C under sterile conditions after reconstitution.
|
Buffer |
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS. |
Preservative |
No Preservative |
Concentration |
LYOPH |
Reconstitution Instructions |
Reconstitute at 0.5 mg/mL in sterile PBS. |
Notes
This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.
Alternate Names for PBEF/Visfatin/NAMPT Antibody (362616) [Unconjugated]
Background
PBEF, also called Nampt or visfatin, is a ubiquitous 52 kDa nicotinamide phosphoribosyltransferase. It is the rate-limiting component in the biosynthesis of NAD+, and functions in the cytoplasm to regulate energy metabolism during stress responses and immune activation. Although it lacks a signal sequence, PBEF appears to be secreted by visceral adipose tissue and functions as a noncompetitive insulin mimetic. Mouse PBEF shows 96% and > 99% aa identity with human and rat PBEF, respectively.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are
guaranteed for 1 year from date of receipt.
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Publications for PBEF/Visfatin/NAMPT Antibody (MAB4044)(1)
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