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PAUF/ZG16B Antibody

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Immunohistochemistry-Paraffin: PAUF/ZG16B Antibody [NBP1-81699] - Staining of human testis shows no positivity in cells in seminiferous ducts as expected.
Immunohistochemistry-Paraffin: PAUF/ZG16B Antibody [NBP1-81699] - Staining of human testis shows no positivity in cells in seminiferous ducts as expected.
Western Blot: PAUF/ZG16B Antibody [NBP1-81699] - Analysis in human cell line MCF-7.
Independent Antibodies: Immunohistochemistry-Paraffin: PAUF/ZG16B Antibody [NBP1-81699] - Staining of human liver, salivary gland, skeletal muscle and testis using Anti-ZG16B antibody NBP1-81699 (A) shows similar ...read more
Orthogonal Strategies: Immunohistochemistry-Paraffin: PAUF/ZG16B Antibody [NBP1-81699] - Analysis in human salivary gland and testis tissues using NBP1-81699 antibody. Corresponding ZG16B RNA-seq data are ...read more
Immunohistochemistry-Paraffin: PAUF/ZG16B Antibody [NBP1-81699] - Staining of human salivary gland shows strong cytoplasmic positivity in glandular cells.
Immunohistochemistry-Paraffin: PAUF/ZG16B Antibody [NBP1-81699] - Staining of human liver shows no positivity in hepatocytes as expected.
Immunohistochemistry-Paraffin: PAUF/ZG16B Antibody [NBP1-81699] - Staining of human skeletal muscle shows no positivity in myocytes as expected.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Validated by:
 

Independent Antibodies

      

Orthogonal Strategies

  

Order Details

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PAUF/ZG16B Antibody Summary

Immunogen
This antibody was developed against Recombinant Protein corresponding to amino acids: AGKMYGPGGGKYFSTTEDYDHEITGLRVSVGLLLVKSVQVKLGDSWDVKLGALGGNTQEVTLQPGEYITKVFVAFQA
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
ZG16B
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Immunohistochemistry-Paraffin 1:200-1:500
  • Western Blot 0.04-0.4 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Control Peptide
PAUF/ZG16B Recombinant Protein Antigen (NBP1-81699PEP)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for PAUF/ZG16B Antibody

  • DKFZp762P2216
  • EC 3.1.2
  • EC 3.4.19.12
  • EECP
  • HRPE773
  • hTrabid
  • JCLN2
  • LOC124220
  • PAUF
  • PRO1567
  • TRABIDubiquitin thioesterase ZRANB1
  • TRAF-binding protein domain
  • ZG16B
  • Zinc finger Ran-binding domain-containing protein 1
  • zinc finger, RAN-binding domain containing 1

Background

PAUF (pancreatic adenocarcinoma upregulated factor), gene name ZG16B (zymogen granule protein 16B), is a 156 amino acid, approximately 20-25 kDa secreted protein that is a member of the jacalin-binding lectin family. PAUF expression is thought to be restricted to primates, but the related ZG16P, which shares approximately 25% amino acid sequence identity, is more widely expressed. Human PAUF is overexpressed in pancreatic adenocarcinoma, binds Toll-like receptors TLR2 and TLR4, and inhibits CXCR4-dependent, TLR2-mediated NF-kB activation. It facilitates tumor growth, adhesiveness, and production of pro-tumorigenic cytokines.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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PAUF/ZG16B Antibody
NBP1-81699
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Bioinformatics

Gene Symbol ZG16B