Western blot shows lysates of HeLa human cervical epithelial carcinoma cell line, MCF-7 human breast cancer cell line, U937 human histiocytic lymphoma cell line, and C2C12 mouse myoblast cell line. PVDF membrane was ...read more
Park7/DJ-1 was detected in immersion fixed HeLa human cervical epithelial carcinoma cell line using Goat Anti-Human/Mouse Park7/DJ-1 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF3668) at 10 µg/mL for 3 ...read more
Genetic Strategies: Western blot shows lysates of HEK293T human embryonic kidney parental cell line and Park7 knockout HEK293T cell line (KO). PVDF membrane was probed with 0.5 µg/mL of Goat Anti-Human/Mouse ...read more
Park7/DJ‑1 was detected in immersion fixed C2C12 mouse myoblast cell line using Goat Anti-Human/Mouse Park7/DJ‑1 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF3668) at 15 µg/mL for ...read more
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70 °C as supplied.
1 month, 2 to 8 °C under sterile conditions after reconstitution.
6 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Preservative
No Preservative
Concentration
LYOPH
Reconstitution Instructions
Reconstitute at 0.2 mg/mL in sterile PBS.
Notes
This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.
Alternate Names for Park7/DJ-1 Antibody [Unconjugated]
DJ1
DJ-1
DJ1FLJ34360
EC 3.4
FLJ27376
FLJ92274
Oncogene DJ1
Park7
Parkinson disease (autosomal recessive, early onset) 7
Parkinson disease protein 7
protein DJ-1
Background
Park7, also known as DJ-1, is a cytoplasmic protein that belongs to the
ThiJ/Pfp1/DJ-1 superfamily of highly conserved proteins that function
as protein chaperones, catalases, proteases and kinases. Park7 is
widely expressed in the brain as well as in peripheral tissues. It
exists as a homodimer that can be localized in the cytoplasm, nucleus
and mitochondria. Park7 is a redox-sensitive protein that has been
ascribed various functions including that as a redox sensor and
antioxidant protein. Mutations in Park7 are associated with a small
percentage of hereditary early onset Parkinson’s disease. Human and
mouse Park7 share 92% amino acid sequence identity.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
Park7/DJ-1: A Reliable Biomarker for Parkinson's Disease? The product of the Parkinson's disease 7 (Park7/DJ-1) gene belongs to the peptidase C56 family of proteins and appears to have two transcriptional variants. It is a positive regulator of androgen receptor-dependent transcription, and some evidence sug... Read full blog post.
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