Reactivity | Hu, Bv, Mu(-), Rt(-)Species Glossary |
Applications | WB, Simple Western, ICC/IF, IHC, KO |
Clone | 4H4 |
Clonality | Monoclonal |
Host | Mouse |
Conjugate | CoraFluor 1 |
Description | CoraFluor(TM) 1 is a high performance terbium-based TR-FRET (Time-Resolved Fluorescence Resonance Energy Transfer) or TRF (Time-Resolved Fluorescence) donor for high throughput assay development. CoraFluor(IM) 1 absorbs UV light at approximately 340 nm, and emits at approximately 490 nm, 545 nm, 585 nm and 620 nm. It is compatible with common acceptor dyes that absorb at the emission wavelengths of CoraFluor(TM) 1. CoraFluor(TM) 1 can be used for the development of robust and scalable TR-FRET binding assays such as target engagement, ternary complex, protein-protein interaction and protein quantification assays. |
Immunogen | Full length recombinant human Park7(DJ-1) expressed in and purified from E. coli. [UniProt# Q99497] |
Localization | Cytoplasm. Nucleus. Mitochondrion. Note: Under normal conditions, located predominantly in the cytoplasm and, to a lesser extent, in the nucleus and mitochondrion. Translocates to the mitochondrion and subsequently to the nucleus in response to oxidative stress and exerts an increased cytoprotective effect against oxidative damage. Detected in tau inclusions in brains from neurodegenerative disease patients. |
Isotype | IgG1 |
Clonality | Monoclonal |
Host | Mouse |
Gene | PARK7 |
Purity | Protein G purified |
Innovator's Reward | Test in a species/application not listed above to receive a full credit towards a future purchase. |
Dilutions |
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Application Notes | Optimal dilution of this antibody should be experimentally determined. |
Storage | Store at 4C in the dark. Do not freeze. |
Buffer | PBS |
Preservative | No Preservative |
Purity | Protein G purified |
Secondary Antibodies |
Isotype Controls |
Research Areas for Park7/DJ-1 Antibody (NBP1-92715CL1)Find related products by research area.
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Park7/DJ-1: A Reliable Biomarker for Parkinson's Disease? The product of the Parkinson's disease 7 (Park7/DJ-1) gene belongs to the peptidase C56 family of proteins and appears to have two transcriptional variants. It is a positive regulator of androgen receptor-dependent transcription, and some evidence sug... Read full blog post. |
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Gene Symbol | PARK7 |