P4HA2 Antibody

This gene encodes a component of prolyl 4-hydroxylase, a key enzyme in collagen synthesis composed of two identical alpha subunits and two beta subunits. The encoded protein is one of several different types of alpha subunits and provides the major part of the catalytic site of the active enzyme. In collagen and related proteins, prolyl 4-hydroxylase catalyzes the formation of 4-hydroxyproline that is essential to the proper three-dimensional folding of newly synthesized procollagen chains. Alternatively spliced transcript variants encoding different isoforms have been described.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 1 confirmed species: Human.

We have publications tested in 1 application: WB.

Showing Publications 1 - 3 of 3.

Publications using NB110-40494	Applications	Species
Gilkes DM, Chaturvedi P, Bajpai S et al. Collagen prolyl hydroxylases are essential for breast cancer metastasis. Cancer Res 2013-06-01 [PMID: 23539444] (WB, Human)	WB	Human
Gilkes DM, Bajpai S, Chaturvedi P et al. HIF-1 Promotes Extracellular Matrix Remodeling under Hypoxic Conditions by Inducing P4HA1, P4HA2, and PLOD2 Expression in Fibroblasts. J Biol Chem 2013-02-19 [PMID: 23423382] (WB, Human)	WB	Human
Berger B, Capper D, Lemke D et al. Defective p53 antiangiogenic signaling in glioblastoma. Neuro Oncol 2010-09-01 [PMID: 20504876]

Images	Ratings	Applications	Species	Date	Details
	5 reviewed by: Verified Customer	WB	Human	01/26/2010	View Summary Application Western Blot Sample Tested MDA-MB-231 Cell Lysate, Sample Amount: 80 ug Species Human Lot A1

Array NB110-40494

• P4HA2 Antibodies
• P4HA2 ELISA Kits
• P4HA2 Lysates
• P4HA2 Proteins