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OXSM Antibody

Images

 
Independent Antibodies: Immunohistochemistry-Paraffin: OXSM Antibody [NBP1-84730] - Staining of human heart muscle, kidney, liver and testis using Anti-OXSM antibody NBP1-84730 (A) shows similar protein ...read more
Western Blot: OXSM Antibody [NBP1-84730] - Analysis in control (vector only transfected HEK293T lysate) and OXSM over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (3.1 kDa) in mammalian HEK293T cells).
Immunocytochemistry/ Immunofluorescence: OXSM Antibody [NBP1-84730] - Staining of human cell line A-431 shows localization to cytosol & mitochondria.
Immunohistochemistry-Paraffin: OXSM Antibody [NBP1-84730] - Staining of human heart muscle shows moderate granular cytoplasmic positivity in cardiomyoctes.
Immunohistochemistry-Paraffin: OXSM Antibody [NBP1-84730] - Staining of human testis shows strong granular cytoplasmic positivity in cells in seminiferous ducts.
Immunohistochemistry-Paraffin: OXSM Antibody [NBP1-84730] - Staining of human kidney shows strong granular cytoplasmic postivity in cells in tubules.
Immunohistochemistry-Paraffin: OXSM Antibody [NBP1-84730] - Staining of human liver shows strong granular cytoplasmic positivity in hepatocytes.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ICC/IF, IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Validated by:
 

Independent Antibodies

       

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OXSM Antibody Summary

Immunogen
This antibody was developed against Recombinant Protein corresponding to amino acids: SSTKGATGHLLGAAGAVEAAFTTLACYYQKLPPTLNLDCSEPEFDLNYVPLKAQEWKTEKRFIGLTNSFGFGGTNATLCIAGL
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
OXSM
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunocytochemistry/ Immunofluorescence 0.25-2 ug/ml
  • Immunohistochemistry 1:50 - 1:200
  • Immunohistochemistry-Paraffin 1:50-1:200
  • Western Blot 0.04-0.4 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. ICC/IF, Fixation Permeabilization: Use PFA/Triton X-100.
Control Peptide
OXSM Protein (NBP1-84730PEP)

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Mouse (88%), Rat (89%)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for OXSM Antibody

  • 3-ketoacyl-acyl carrier protein synthase
  • 3-oxoacyl-[acyl-carrier-protein] synthase, mitochondrial
  • 3-oxoacyl-ACP synthase, mitochondrial
  • acyl-malonyl acyl carrier protein-condensing enzyme
  • beta-ketoacyl synthase
  • Beta-ketoacyl-ACP synthase
  • EC 2.3.1
  • EC 2.3.1.41
  • FASN2D
  • FLJ20604
  • KASI
  • KS3-oxoacyl-acyl-carrier-protein synthase
  • type II mitochondrial beta-ketoacyl synthase

Background

OXSM is a mitochondrial beta-ketoacyl synthase (EC 2.3.1.41) involved in mitochondrial fatty acid synthesis. It is required for catalysis of the chain-elongating condensation reaction (Zhang et al., 2005 [PubMed 15668256]).[supplied by OMIM]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

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Bioinformatics

Gene Symbol OXSM