Independent Antibodies: Western Blot: MAP4K6 Antibody [NBP1-22990] - Whole cell lysate from HeLa and mouse NIH3T3 cells at 0.04 mcg/ml (A) and 1 mcg/ml (B) and used for IP at 3 mcg/mg lysate.
The immunogen recognized by this antibody maps to a region between residue 775 and 825 of human misshapen-like kinase 1 using the numbering given in entry NP_722549.2 (GeneID 50488).
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
MINK1
Purity
Immunogen affinity purified
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Mitogen-activated protein kinase kinase kinase kinase 6
serine/threonine protein kinase
YSK2
ZC3
Background
MINK1 (misshapen/NIKs-related kinase 1) is a member of the germinal center kinase (GCK) family that are homologous to the yeast sterile 20 (Ste20) kinases. GCKs function in the activation of the JNK pathway. MINK1 has been found to activate the JNK pathway and may have a role in modulating cytoskeletal organization, cell adhesion, and cell migration during development.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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