KCNE1 Antibody (5B12)

This product is produced by and distributed for Abnova, a company based in Taiwan.

The product of this gene belongs to the potassium channel KCNE family. Potassium ion channels are essential to many cellular functions and show a high degree of diversity, varying in their electrophysiologic and pharmacologic properties. This gene encodes a transmembrane protein known to associate with the product of the KVLQT1 gene to form the delayed rectifier potassium channel. Mutation in this gene are associated with both Jervell and Lange-Nielsen and Romano-Ward forms of long-QT syndrome. Alternatively spliced transcript variants encoding the same protein have been identified.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Showing Publications 1 - 4 of 4.

Publications using H00003753-M01	Applications	Species
Zankov DP, Salloum FN, Jiang M et al. Chronic in vivo angiotensin II administration differentially modulates the slow delayed rectifier channels in atrial and ventricular myocytes. Heart Rhythm 2018-08-01 [PMID: 30075281]
Jiang M, Wang Y, Tseng G et al. Adult Ventricular Myocytes Segregate KCNQ1 and KCNE1 to Keep the IKs Amplitude in Check Until When Larger IKs Is Needed. Circ Arrhythm Electrophysiol. 2017-06-15 [PMID: 28611207]
Wang Y, Zankov DP, Jiang M et al. [Ca2+]i Elevation and Oxidative Stress Induce KCNQ1 Protein Translocation from the Cytosol to the Cell Surface and Increase Slow Delayed Rectifier (IKs) in Cardiac Myocytes. J Biol Chem. 2013-10-18 [PMID: 24142691]
Wu D, Jiang M, Zhang M et al. KCNE2 is colocalized with KCNQ1 and KCNE1 in cardiac myocytes and may function as a negative modulator of I(Ks) current amplitude in the heart. Heart Rhythm. 2006-08-25 [PMID: 17161791]

Array H00003753-M01

• KCNE1 Antibodies
• KCNE1 Lysates