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OATP1B3/SLCO1B3/OATP8 Antibody [Janelia Fluor® 635]

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Summary
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    • Catalog Number
      NBP2-98474JF635
    • Availability
      Product Discontinued

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OATP1B3/SLCO1B3/OATP8 Antibody [Janelia Fluor® 635] Summary

Immunogen
Produced in rabbits immunized with E. coli-derived Human OATP1B3/SLCO1B3/OATP8 fragment.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
SLCO1B3
Purity
Antigen and protein A Affinity-purified
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Applications/Dilutions

Dilutions
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Antigen and protein A Affinity-purified

Notes



Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for OATP1B3/SLCO1B3/OATP8 Antibody [Janelia Fluor® 635]

  • Liver-specific organic anion transporter 2
  • liver-specific organic anion transporter 3TM13
  • LST2
  • LST-2
  • LST3
  • OATP1B3
  • OATP1B3LST-3TM13
  • OATP8
  • OATP-8
  • Organic anion transporter 8
  • organic anion transporter LST-3c
  • Organic anion-transporting polypeptide 8
  • SLC21A8
  • SLCO1B3
  • solute carrier family 21 (organic anion transporter), member 8
  • Solute carrier family 21 member 8
  • solute carrier organic anion transporter family member 1B3
  • solute carrier organic anion transporter family, member 1B3

Background

The OATPs (organic anion transporter polypeptides) are a family of transport proteins that have been found to mediate the uptake of organic ions into hepatocyte cells. These proteins fall into the solute carrier family 21A (SLC21A), and are expressed in liver, kidney, and brain. These polypeptides are involved in the excretion of potentially toxic compounds and therefore play a role in the overall detoxification system of the body. Unlike other members of the OATP family, OATP2 and 8 have been detected exclusively in the liver, and there is an 80% amino acid sequence homology between these polypeptides. Other names for OATP2 include SLC21A6, OATP-C, and LST-1.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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OATP8 - A membrane transport protein responsible for cancer drug uptake
Human hepatocytes express important transport proteins that are responsible for the uptake and removal of organic anions from the blood. These proteins are members of the organic anion-transporting polypeptide (OATP) family and are essential for pr...  Read full blog post.
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Bioinformatics

Gene Symbol SLCO1B3