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NUP214 Antibody

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Western Blot: NUP214 Antibody [NBP3-41180] - Sample: Recombinant NUP214, Mouse.
Western Blot: NUP214 Antibody [NBP3-41180] - Sample: Recombinant NUP214, Mouse.
Immunohistochemistry-Paraffin: NUP214 Antibody [NBP3-41180] - Used in DAB staining on fromalin fixed paraffin- embedded Kidney tissue

Product Details

Summary
Reactivity MuSpecies Glossary
Applications WB, ICC/IF, IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
0.5 mg/ml

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NUP214 Antibody Summary

Immunogen
Immunized with recombinant Mouse NUP214 (Uniprot#: Q80U93; Ser601-Arg868 (Uniprot#: Q80U93)
Clonality
Polyclonal
Host
Rabbit
Gene
NUP214
Purity
Antigen and protein A Affinity-purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Immunocytochemistry/ Immunofluorescence 5-20ug/mL
  • Immunohistochemistry 5-20ug/mL
  • Western Blot 0.5-2ug/mL

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
0.01M PBS, pH7.4, 50% glycerol
Preservative
0.05% Proclin 300
Concentration
0.5 mg/ml
Purity
Antigen and protein A Affinity-purified

Alternate Names for NUP214 Antibody

  • 214 kDa nucleoporin
  • CAINputative oncogene
  • D9S46Enuclear pore complex protein Nup214
  • KIAA0023
  • MGC104525
  • N214
  • nucleoporin 214kD (CAIN)
  • nucleoporin 214kDa
  • Nucleoporin Nup214
  • p250
  • Protein CAN

Background

The nuclear pore complex is a massive structure that extends across the nuclear envelope, forming a gateway that regulates the flow of macromolecules between the nucleus and the cytoplasm. Nucleoporins are the main components of the nuclear pore complex in eukaryotic cells. This gene is a member of the FG-repeat-containing nucleoporins. The protein encoded by this gene is localized to the cytoplasmic face of the nuclear pore complex where it is required for proper cell cycle progression and nucleocytoplasmic transport. The 3' portion of this gene forms a fusion gene with the DEK gene on chromosome 6 in a t(6,9) translocation associated with acute myeloid leukemia and myelodysplastic syndrome.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol NUP214