Species: Hu
Applications: WB, IHC, IP
Host: Rabbit Polyclonal
Species: Hu, Mu, Rt
Applications: WB, ICC/IF
Host: Rabbit Polyclonal
Species: Mu
Applications: WB, ICC/IF, IHC
Host: Rabbit Polyclonal
Species: Hu
Applications: WB, ELISA, MA, PAGE, AP
Species: Hu
Applications: AC
Description
The nuclear pore complex is a massive structure that extends across the nuclear envelope, forming a gateway that regulates the flow of macromolecules between the nucleus and the cytoplasm. Nucleoporins are the main components of the nuclear pore complex in eukaryotic cells. This gene is a member of the FG-repeat-containing nucleoporins. The protein encoded by this gene is localized to the cytoplasmic face of the nuclear pore complex where it is required for proper cell cycle progression and nucleocytoplasmic transport. The 3' portion of this gene forms a fusion gene with the DEK gene on chromosome 6 in a t(6,9) translocation associated with acute myeloid leukemia and myelodysplastic syndrome.
Bioinformatics
Uniprot |
Human Human Human |
Product By Gene ID |
8021 |
Alternate Names |
- 214 kDa nucleoporin
- CAINputative oncogene
- D9S46Enuclear pore complex protein Nup214
- KIAA0023
- MGC104525
- N214
- nucleoporin 214kD (CAIN)
- nucleoporin 214kDa
- Nucleoporin Nup214
- p250
- Protein CAN
|
Research Areas for NUP214
Find related products by research area and learn more about each of the different research areas below.
Angiogenesis