Nup153 Antibody

Nuclear pore complexes are extremely elaborate structures that mediate the regulated movement of macromolecules between the nucleus and cytoplasm. These complexes are composed of at least 100 different polypeptide subunits, many of which belong to the nucleoporin family. Nucleoporins are pore complex-specific glycoproteins characterized by cytoplasmically oriented O-linked N-acetylglucosamine residues and numerous repeats of the pentapeptide sequence XFXFG. The protein encoded by this gene has three distinct domains: a N-terminal region within which a pore targeting domain has been identified, a central region containing multiple zinc finger motifs, and a C-terminal region containing multiple XFXFG repeats.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 1 confirmed species: Human.

We have publications tested in 3 applications: ICC/IF, WB, Western Blot.

Showing Publications 1 - 4 of 4.

Publications using NB100-93329	Applications	Species
Wei G, Iqbal N, Courouble VV et al. Prion-like low complexity regions enable avid virus-host interactions during HIV-1 infection Nature Communications 2022-10-06 [PMID: 36202818] (Western Blot)	Western Blot
Znaidi R, Massiani-Beaudoin O, Mailly P et al. Nuclear translocation of LINE-1 encoded ORF1p alters nuclear envelope integrity and disrupts nucleocytoplasmic transport in neurons bioRxiv 2023-08-14 (ICC/IF, Human)	ICC/IF	Human
Fiserova J, Maninova M, Sieger T et al. Nuclear pore protein TPR associates with lamin B1 and affects nuclear lamina organization and nuclear pore distribution Cell. Mol. Life Sci. 2019-02-14 [PMID: 30762072] (WB, Human)	WB	Human
Wan G, Zhang X, Langley RR et al. DNA-Damage-Induced Nuclear Export of Precursor MicroRNAs Is Regulated by the ATM-AKT Pathway. Cell Rep 2013-06-27 [PMID: 23791529] (WB, Human)	WB	Human

Images	Ratings	Applications	Species	Date	Details
Enlarge	5 reviewed by: Verified Customer	WB	Human	01/31/2018	View Summary Application Western Blot Sample Tested MDA-MB-231 nuclear extracts Species Human Lot A1 Comments Comments Knockdown of NUP153 in MDA-MB-231 breast cancer cells. Lane 1: ladder. Lane 2: Scramble Control Lane 3: NUP153 knockdown. Substantially reduced protein detection in knockdown sample and not in scramble control reflect antibody's unique specificity for Nup153. This image was submitted by customer review.
	4 reviewed by: Verified Customer	WB	Human	12/23/2014	View Summary Application Western Blot Sample Tested See PMID 23791529 Species Human

Array NB100-93329

• Nup153 Antibodies
• Nup153 Proteins