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NMDAR2A Antibody (S327-95)

Images

 
Western Blot: NMDAR2A Antibody (S327-95) [NBP2-22405] - Western Blot analysis of Monkey COS cells transfected with GFP-tagged NMDAR2A showing detection of ~170 kDa NMDAR2A protein using Mouse Anti-NMDAR2A Monoclonal ...read more
Immunocytochemistry/ Immunofluorescence: NMDAR2A Antibody (S327-95) [NBP2-22405] - Immunocytochemistry/ Immunofluorescence analysis using Mouse Anti-GluN2A/NR2A Monoclonal Antibody, Clone S327-95 (NBP2-22405). Tissue: ...read more
Immunocytochemistry/ Immunofluorescence: NMDAR2A Antibody (S327-95) [NBP2-22405] - Tissue: Neuroblastoma cell line SK-N-BE. Species: Human. Fixation: 4% Formaldehyde for 15 min at RT. Primary Antibody: Mouse ...read more
Immunocytochemistry/ Immunofluorescence: NMDAR2A Antibody (S327-95) [NBP2-22405] - Immunocytochemistry/ Immunofluorescence analysis using Mouse Anti-GluN2A/NR2A Monoclonal Antibody, Clone S327-95 (NBP2-22405). Tissue: ...read more

Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, ICC/IF, IHC
Clone
S327-95
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Concentration
1 mg/ml

NMDAR2A Antibody (S327-95) Summary

Immunogen
Fusion protein amino acids 75-325 (extracellular N-terminus) of rat GluN2A/NR2A
Localization
Cell Membrane , Cell Junction
Specificity
Detects approx 170kDa. Does not react with NR2B.
Isotype
IgG2a
Clonality
Monoclonal
Host
Mouse
Gene
GRIN2A
Purity
Protein G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry
  • Western Blot 1:1000
Application Notes
1 ug/ml of GluN2A/NR2A Antibody was sufficient for detection o GluN2A/NR2A in 20 ug of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary Antibody.
Publications
Read Publications using NBP2-22405.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.4), 50% Glycerol
Preservative
0.09% Sodium Azide
Concentration
1 mg/ml
Purity
Protein G purified

Alternate Names for NMDAR2A Antibody (S327-95)

  • GluN2A
  • glutamate receptor, ionotropic, N-methyl D-aspartate 2A
  • hNR2A
  • NMDA receptor subtype 2A
  • N-methyl D-aspartate receptor subtype 2A
  • N-methyl-D-aspartate receptor subunit 2A
  • subunit epsilon-1

Background

The ion channels activated by glutamate are divided into two classes. Those that are sensitive to N-methyl-D-aspartate (NMDA) are designated NMDA receptors (NMDAR) while those activated by kainate and a-amino-3-hydroxy-5-methyl-4-isoxalone propionic acid (AMPA) are known as kainate/AMPA receptors (K/AMPAR). NMDA receptors are among the most studied receptors in neuroscience because they are involved in neuronal cell development and plasticity, a cellular correlate for learning. NMDA receptors are also implicated in several disorders of the central nervous system including epilepsy and ischemic neuronal cell death. NMDA receptors also appear to be a target for ethanol at physiological concentrations and therefore may play a significant role in alcoholism.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for NMDAR2A Antibody (NBP2-22405)(2)

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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol GRIN2A
Uniprot